This guide outlines the extent of drug use and alcohol problems on college campuses and recommends five strategies for institutions of higher education: (1) develop clear policies concerning alcohol and other drugs; (2) enforce alcohol and other drug regulations; (3) provide alcohol and other drug education and prevention programs; (4) ensure intervention and referral for treatment of students, faculty, and staff; and (5) assess attitudes and behavior toward alcohol and other drugs as well as the effectiveness of education, prevention, intervention, and treatment programs. The guide recommends specific actions that college presidents and governing boards can take to carry out each strategy, and includes a checklist for pursuing each strategy. Appendixes contain: membership guidelines and standards of the Network of Colleges and Universities Committed to the Elimination of Drug and Alcohol Abuse, the Drug-Free Schools and Communities Act Amendments of 1989, and guidelines for beverage alcohol marketing on college and university campuses of the Inter-Association Task Force on Campus Alcohol Policy Issues. Includes nine references. (JDD)