This report was developed to address institutional biosafety committees' implementation of federal guidelines applicable to the environmental release of genetically engineered organisms. These committees are from universities, companies, and other organizations that are using recombinant DNA technology in their laboratories. The committees are responsible for reviewing research proposals using this technology to insure proper containment of recombinant organisms and the safety of laboratory personnel. This report is on the biosafety committees': (1) membership composition; (2) functions and activity levels; (3) implementation of the National Institute of Health guidelines for research involving recombinant DNA molecules; and (4) role in federal regulation of genetically engineered organisms. In addition, the report deals with the involvement of Montana State University's biosafety committee concerning a recent and deliberate release of genetically engineered organisms without prior approval by the committee or by the Environmental Protection Agency. (TW)