Objectives and outcome data of a University of Cincinnati College of Medicine program, which serves infants at risk for developmental disorders and their mothers, are presented. The Infant Stimulation/Mother Training Program for premature, low birthweight infants is designed to meet the following service objectives: 1) identify and recruit high-risk mother-infant pairs after delivery; 2) modify the environment of the neonatal special care nursery to actively involve parents in infant care; 3) counsel, support, and provide medical information to parents; 4) provide services following the infant's discharge, including weekly mother-infant classes and home visiting; 5) provide medical followup clinic services integrated with social service, nutrition, and psychological interventions, as well as referrals to specialty clinics and educational intervention programs; 6) provide continuity of service from birth to 3 years; 7) provide training and practicum experiences for medical, nursing, and graduate students; 8) gain public support for the concept of primary prevention; and 9) develop curriculum materials, media presentations, and publications. Program accomplishments are detailed, including the names of out-of-town participating hospitals; data on inservice training and consultation; and program evaluation findings on the impact of the nurses' outreach training. (SEW)