This manual is intended as a resource for anyone involved in planning, developing, and/or operating a horticultural training or work co-op program for the handicapped. Following an introductory chapter, the manual is divided into three parts with the greatest weight given to the second part. Part I elaborates on development of the horticulture therapy and rehabilitation field and puts into perspective the breadth of the current horticultural programs. Part II consists of the fundamental building blocks of the program. It includes guidelines for leadership, administration, community assessment, funding, personnel, and federal regulations. General training guidelines pertaining to admission, evaluation, and wage determination are also considered. Four program models are described: greenhouse, plant sales, grounds maintenance, and contracting. The greenhouse and grounds maintenance program models are broken down into prevocational training, vocational training, and work co-op operations, and the requisite needs of planning, management, training, business, facilities, equipment, staff, etc., are discussed. Part III briefly presents a history and overview of the Melwood Horticultural Training Center, Inc., to exemplify the models presented earlier. Appendixes, amounting to approximately one-fourth of the manual, include sample personnel job descriptions, universities with horticultural therapy programs, curricula, and training and evaluation. (YLB)