Data are from a large scale experimental study which was designed to evaluate a multimethod problem solving approach to obesity. Obese adult volunteers (N=90) were randomly assigned to three groups: maximal treatment, minimal treatment, and no treatment control. In the two treatment groups, subjects were exposed to bibliographic material and therapeutic sessions. During the first six months of treatment, maximal subjects were seen weekly whereas minimal subjects were seen once every three weeks. In addition to height and weight, experimental subjects were assessed on the following factors: somatotype, serum lipids, blood pressure, exercise stress (EKG), pulmonary function, densitometric body fat, skinfold estimated body fat, ultrasonic estimation of body fat, orthostasis, cellular biopsy (to assess adipocyte size and number), girth measurements, daily activity level (via pedometer), daily energy intake (via self-recording), familial history, nutrition knowledge, exercise knowledge, weight loss attitudes and attributions, plus a variety of psychometric scales which range from depression and marital adjustments to personality profiles and the restraint scale. These numerous factors were measures in an attempt to identify predictor variables which correlate with differential responsiveness to treatment. The overall findings from the study are presented, along with some implications for further research and treatment. (Author)