Computers have effected a comprehensive transformation of chemistry. Computers have greatly enhanced the chemist's ability to do model building, simulations, data refinement and reduction, analysis of data in terms of models, on-line data logging, automated control of experiments, quantum chemistry and statistical and mechanical calculations, and information storage including retrieval and the capacity for dynamic visual display. A recent conference addressed itself to the following aims: (1) provide a national forum for the impact of computers on chemistry; (2) encourage more investigation on computers; (3) make known the present status and the potential of computer-assisted instruction (CAI) in chemistry; and (4) inspire further examination of the chemistry curriculum in light of recent advances in computer technology. The conference report is a collection of 80 papers divided into the following categories: data fitting; curve fitting and band analysis of spectra; structure determination; CAI; computer technology in theoretical chemistry; chemistry curriculum development; communications in the field of chemistry; computer control of experiments; the use of A Programing Language (APL) in the undergraduate curriculum; and information systems. (EMH)