The National Institute on Drug Abuse presents this report as the fifth in a series intended to summarize the empirical research findings and major theoretical approaches relating to the the issues of drug use and abuse. Included in this volume are summaries of the major research findings concerning the effects of nonmedical drug use on pregnancy. Research findings on the genetic, epidemiological, childbirth and neonatal effects of drug use are examined, especially in relation to the use of LSD, heroin and methadone. The summary of each study is formulated and detailed to provide the reader with the purpose, methodology, findings and conclusions of the study. (Author/SJL)