This study is the result of a project of the Committee on Design, Construction and Equipment of Laboratories, Division of Chemistry and Chemical Technology, of the National Academy of Sciences. The problems and methods of planning, designing and constructing varying types of chemical laboratories for research and developmental buildings are discussed, in conjunction with guidelines, standards, and performance criteria for their equipment and facilities. Techniques of organizing factors and principles for selecting sites, building materials, equipment, and furniture are discussed with regard to the various types of services required. Laboratory planning based on occupational health and safety is emphasized and becomes an integral part of both the technical and non-technical types of facility discussed. Facility and planning requirements for lecture, teaching and academic laboratories are given, along with descriptions of industrial, governmental and academic laboratory buildings built in the past. An appendix, photographs, floor plans and specifications are included. (TG)