To obtain baseline information about the relationship among performances in education programs, certification examinations, and working situations, the 358 cytotechnologists who took the 1965 certification examination in exfoliative cytology were selected for study. Based on questionnaires and other information concerning education and clinical experience, some conclusions were: (1) Almost all of the 306 cytotechnologists for whom information about college science courses was available had credit hours on at least one basic biological science; more than 60 percent took courses in inorganic chemistry, bacteriology, and mathematics; half or fewer had credit in anatomy, physiology, organic chemistry, physics, and other science courses, (2) There was a tendency for those who passed the certification examination to have credit hours in a greater variety of science courses and to receive satisfactory grades in these courses than those who failed the certification examination, (3) There was a direct relationship between evaluations of clinical study and performance in the certification examination, and (4) A higher percentage of failures occurred among cytotechnologists who began their clinical study between 1958 and 1961. (JK)