The bulletin was prepared as a general guide to encourage the use of safe practices in science laboratories in Florida schools. The guide begins with an outline of recommended emergency procedures. Chapter I discusses the importance of safety in the science program. Chapter II discusses handling and storage of equipment, and designing laboratory facilities. Chapter III discusses safety with particular types of laboratory activities including those involving plants, animals, heat, electricity, radioactive materials, and chemicals. Ten appendices, including a list of Poison Control Centers in the State of Florida, are included. (BC)