With the growing emphasis on social entrepreneurship (SE), many universities are delivering social entrepreneurship courses (SECs) to develop students' social awareness and aspirations, and socially entrepreneurial behaviors. This study investigates the extent to which the entrepreneurial ecosystem (EE), entailing entrepreneurism at individual, university and regional levels, may impact on universities' decisions to offer SECs to business students. Using data from 501 US-based, AACSB-accredited business schools, the finding indicates the importance of the universities' EE and entrepreneurialism at multi-levels in their commitment to SECs.