In this paper, we present a concise and technique-heavy route to the synthesis of dimedone for a second-year organic chemistry curriculum. Our preparation of dimedone guides students through a Michael addition followed by a Dieckmann cyclization, basic ester hydrolysis, and thermal decarboxylation, while allowing time for mechanistic discussion…

Metabolic Control Analysis (MCA) is a systems biology approach that measures the control of a metabolic step on the overall flux of a metabolic pathway. In undergraduate courses in biochemistry, learning of MCA can be encouraged by experimental activities demonstrating practical applications of the MCA theory. In this work, we present a laboratory…

Calorimetry is a central concept in the first semester general chemistry curriculum, and constant pressure (coffee-cup) calorimetry is a common experiment in the laboratory. However, constant volume (bomb) calorimetry is traditionally reserved for the physical chemistry laboratory. This article describes the advantages of incorporating bomb…

In this laboratory experiment, students modify a series of surfaces and explore the effects of varying surface chemistry and texture on wettability by different probe liquids. Students begin by building a simple contact angle goniometer utilizing their mobile phone cameras. Next, they contrast the wettability of planar glass substrates…

Electrochemistry plays a crucial role in our everyday lives. It allows us to power our phones and cars and allows for the real-time monitoring of blood glucose levels. While electrochemistry is of vital importance and is a long-established field of chemistry, it is often neglected in modern curricula for STEM courses. Herein, we show that hands-on…

This paper reports the quantification of Ca, Mg, and Fe as micronutrients in different vegetables (spinach, sugar beets, and carrots) from raw and processed samples. Simple extraction procedures, titrations, and spectrophotometric analysis were used to determine the amounts of micronutrients before and after cooking. From the obtained results, an…

In recent years, pedagogical advancements have allowed the adoption of more engaging forms of course assignments to help students better understand and communicate chemistry. In this context, informational graphics, known as infographics, emerge as an effective teaching aid in educational settings and in disseminating scientific content to the…

Chemists have always designed and deployed cross-disciplinary approaches that interface chemistry with other disciplines to proffer solutions to many human problems. We designed a laboratory experiment that implements chemistry concepts in a biological model to prime undergraduate students to appreciate interdisciplinarity as an approach to…

Cycloadditions in combination with multicomponent reactions are among the most valuable synthetic tools used by organic chemists to construct cyclic and heterocyclic compounds in a straightforward way. Although cycloadditions, such as the Diels--Alder reaction, are mainly covered in basic and advanced organic courses for undergraduate students,…

Concepts of experimentation and measurement are explored using statistics educational fun items and illustrated by sharing our process in conducting an experiment on cartoon captions.

Multistep synthesis is a key capstone experience in organic laboratory instruction. Here, a four-step synthesis of avobenzone, an active component in sunscreens, has been developed that can be completed in two 4 h laboratory periods. This synthesis incorporates green principles and includes an aldol condensation, electrophilic addition of bromine…

Single slit diffraction and the thermal expansion of materials are common components of an undergraduate physics course, though these topics are often taught independently in both lectures and laboratory based courses. Higher levels of cognitive domains can be achieved by building on these established topics and combining them into a single…

A popular introductory physics laboratory experiment is one focusing on Snell's law. This is straightforward to complete with lasers and prisms, but here we present an alternative version that guides the students through some of the major historical developments, recreating and analyzing significant experiments. The discovery of Snell's law has a…

The possibility of conducting laboratory experiments at home without using commercially available kits, which might also be overly expensive, seems to be a suitable approach for a distance chemistry laboratory. Thus, several hands-on experiments with household supplies have been developed aiming at fostering students' laboratory competencies, as…

So-called "Color Wonder" markers contain colorless dyes that only display color when used to mark on special "Color Wonder" paper. These markers make use of leuco dyes that only develop color in the presence of acid. These markers provide science educators with a novel chemical system that can be implemented in inquiry-based…