Scholars and researchers are increasingly calling attention to the need for community-based coalitions to become more inclusive of local residents and engage those most directly affected by the issues. One population, however, often remains the recipient of services as opposed to partners or leaders in community change initiatives: youth. Over the past several years in Ohio, adults convening and facilitating youth-led programs have been transforming their work by utilizing the Youth Empowerment Conceptual Framework and the Substance Abuse and Mental Health Services Administration's Strategic Prevention Framework to empower young people and ensure their equitable participation in community change efforts. This article provides an overview of Ohio's statewide youth-led initiative, highlighting how adult allies engaged young people in a data-driven strategic planning process and intentionally selected and implemented strategies designed to affect the health of their local communities. This initiative provides key insights into the Collaborating for Equity and Justice Principles 4, 5, and 6.