While there is no official definition, making is generally thought of as turning ideas into products through design, invention, and building. Support is growing for integrating making into science, technology, engineering, and mathematics (STEM) education. Making can help high school students explore science concepts and phenomena, yet, lacking training and experience, many science teachers are reluctant to add making to their curriculum. This article describes six elements of making, provides a matrix to assist teachers, and offers a sample chemistry lesson for context.