A major characteristic of age-related changes in memory in rodents is an increase in the rate of forgetting of new information, even when tests given soon after training reveal intact memory. Interference with CREB functions similarly results in rapid decay of memory. Using quantitative immunocytochemistry, the present experiment examined the…

We designed and implemented curriculum intended to be used by students in an algebra-based introductory physics laboratory course. Our curricular goal was to foster, through observations in the lab, a coherent framework in students' understanding of general principles presented in the introductory mechanics course, while addressing known student…

Detection of biologically active compounds is one of the most important topics in molecular biology and biochemistry. One of the most promising detection methods is based on the application of surface plasmon resonance for label-free detection of biologically active compounds. This method allows one to monitor binding events in real time without…

This qualitative study examines one professional development program and how this experience affects teachers' thoughts about planning and science teaching practices specific to the elements focused on during the program. The program supports 13 American K-12 teachers, selected from across the nation, to spend six weeks with a mentor scientist in…

For teachers, a common difficulty when introducing scientific thinking is finding ways to engage the participation of the students. Because most scientific problems require at least some specialized knowledge to formulate and solve, it can be hard to go beyond merely discussing the steps of the scientific method and illustrating them with the…

This article provides a first-person account of a training program in group dynamics. It is deliberately written in the first-person to capture the highly personal nature of group dynamic analysis. Proceeding through an intensive account of six days of T-groups, module facilitation, and facilitator feedback sessions, the author examines painful…

A well-constructed, step-by-step protocol is a critical starting point for teaching undergraduates new techniques, an important record of a lab's standard procedures, and a useful mechanism for sharing techniques between labs. Many research labs use websites to archive and share their protocols for these purposes. Here we describe our experiences…

There is an increasing need for students in the biological sciences to build a strong foundation in quantitative approaches to data analyses. Although most science, engineering, and math field majors are required to take at least one statistics course, statistical analysis is poorly integrated into undergraduate biology course work, particularly…

A trainerless laboratory model wherein the trainer never attends is presented. The discussion includes the advantages and disadvantages of the model, evidence for its effectiveness, and implications for the future of training. (Author)

Responding to the concern from our faculty that undergraduate students do not have robust laboratory skills, we designed and implemented a strategy to individually teach and assess the manipulative skills of students in first-year laboratories. Five core laboratory skills were selected for the course entitled Human Biology, a large, first-year…

Digestion of DNA with restriction enzymes, calculation of volumes and concentrations of reagents for reactions, and the separation of DNA fragments by agarose gel electrophoresis are common molecular biology techniques that are best taught through repetition. The following open-ended, investigative laboratory exercise in plasmid restriction…

Here, we describe a laboratory experiment as part of an upper-level vertebrate physiology course for biology majors to investigate the physiological response of vertebrates to osmoregulatory challenges. The experiment involves measuring plasma osmolality and Na[superscript +] -K[superscript +] -ATPase activity in gill tissue of teleost fish…

This appendix contains descriptions of several laboratory-type experiences suitable for a training program for educational leaders. Activities include a series of 10-minute microlab experiences, lecturettes followed by skill sessions, T-Group games, and various other experiences to stimulate self-exploration, group intercommunication, observation,…

Changing culture requires interventions invalidating old processes and conditions that facilitate the creation of new self validating processes. The personal growth laboratory becomes a temporary system of new self validating processes. Prepared for a conference on Intensive Small Group Process sponsored by Foundations Fund for Research in…