The purpose of this study is to determine the variables that affect career transition levels of Turkish and U.S. participants. For this purpose, 336 (n[subscript U.S.] = 151; n[subscript Turkey] = 185) participants who reported their socio-economic level as middle experiencing career transition at least for 2-3 months are included in the study. According to the Career Transition Model, hopelessness and trait anxiety affect Turkish participants' career transition significantly, but do not have such an effect for U.S. participants. In addition to this, social support does not affect career transition of Turkish participants significantly, and this is also true for U.S. participants. Finally, the Career Transition Model does not show a significant difference based on culture.