An experiment in teaching students to use the literature to devise and defend a plan for novel research is presented as part of a graduate-level course in heterocyclic chemistry. Students in three successive iterations of the course completed an assignment during which they were assigned novel heterocyclic cores that were selected by varying or…

Fear can potently inhibit ongoing behavior, including reward-seeking, yet the neural circuits that underlie such suppression remain to be clarified. Prior studies have demonstrated that distinct subregions of the rodent medial prefrontal cortex (mPFC) differentially affect fear behavior, whereby fear expression is promoted by the more dorsal…

The Pre-College Summer Program at the University of Connecticut is designed to introduce upper-level high school students (rising juniors and seniors) to college life by allowing them to live on campus for a week while taking a college-level course. Within the context of this program, we developed a class designed to introduce high school students…

Fragment-based drug design (FBDD) is a promising methodology to find quality drug leads. It is important in the curriculum of a drug design course due to its impact on drug discovery. However, teaching FBDD and its use by students remain challenging in most cases. A web-based laboratory class to teach FBDD in the form of our copyrighted workshops…

Zinc oxide is a common additive in food, cosmetics, and medicines. Here, we describe the validation of methods to analyze two pharmaceutical samples containing ZnO--talc powder and dermal ointment--by ethylenediaminetetraacetic acid (EDTA) titration. The methods developed were implemented as a practical class to students of a Quantitative Analysis…

The Elicited Imitation Test (EIT) is widely recognized for its reliability in research settings as a proficiency assessment tool. However, there exists a need to examine its predictive validity in English as a Foreign Language (EFL) classrooms. This study investigates the extent to which the EIT, alongside the Oxford Placement Test (OPT), can…

The European Open Platform for Prescribing Education (EurOP2E) seeks to improve and harmonize European clinical pharmacology and therapeutics (CPT) education by facilitating international collaboration and sharing problem-based, online, open educational resources. The COVID-19 pandemic forced teachers to switch to virtual modalities, highlighting…

Purpose: This paper aims to examine how distinct sequences of organizational learning types (experiential and vicarious) underpin processes of exploratory versus exploitative innovation. Design/methodology/approach: Data collection consists of 16 interviews conducted with senior personnel at two firms in the biopharmaceutical sector, with…

What constitutes an ideal prelicensure nursing curriculum is not well understood. Specifically, what are the strategic curricular sequencing and curricular themes or focus might be included to contribute to producing high quality graduates? The purpose of this qualitative multiple case study investigation was to look at successful programs and…

New assessment types that include multimodal and digital elements are increasingly being used to assess university students' 'soft skills' such as communication, as well as their science content knowledge. However, very little is known about how or how well such products assess communicative elements, particularly when these elements are so…

While science students are well prepared for careers in biotechnology and pharmaceutical sciences in terms of technical expertise and critical thinking, they rarely have an opportunity to practice the due diligence required for success in industry in their coursework. This includes framing their expertise as solutions to challenges a company may…

This article describes three historical cases of drug discovery and how they were adapted as examples to teach chemical analysis to students pursuing a pharmacy (UK MPharm) and pharmaceutical sciences (BSc Pharmaceutical Sciences) degree. The selected cases were the synthesis of benzodiazepines and the discovery of warfarin and neuromuscular…

In an academic semester, living in social isolation and under restrictions of the pandemic, we organized weekly multidisciplinary seminars from a postgraduate course program in Curitiba, Southern Brazil, integrating students from different regions of Brazil and South America. Outstanding researchers from Brazil, Germany, France, Argentina, Mexico,…

Loss of 7 weeks of organic chemistry laboratory work, including 3-4 weeks that would have been used for a CURE, prompted the creation of a literature review project in which students investigated synthetic routes to drug molecules of molecular weight 180 g/mol or less. The students wrote a 5-10 page paper and then made videotaped presentations…

Throughout the different phases of a drug development program, randomized trials are used to establish the tolerability, safety and efficacy of a candidate drug. At each stage one aims to optimize the design of future studies by extrapolation from the available evidence at the time. This includes collected trial data and relevant external data.…