Background: Clustered randomized controlled trials are commonly used to evaluate the effectiveness of treatments. Frequently, stratified or paired designs are adopted in practice. Fogarty (2018) studied variance estimators for stratified and not clustered experiments and Schochet et. al. (2022) studied that for stratified, clustered RCTs with…

The double-indicator method is often used in the analysis of Na[subscript 2]CO[subscript 3], NaHCO[subscript 3], and NaOH mixtures (carbonate mixtures). In this method, the determination of the volumes at the first and second equivalence points plays a crucial role in analyzing the composition and content of the carbonate mixtures. Here, LabVIEW…

An engaging, simple, and cost-effective laboratory experiment has been implemented at our institution to teach undergraduate chemistry students about cyclic voltammetry and electrochemistry in general. This experiment involves the application of cyclic voltammetry to analyze a sample of acetaminophen (APAP) with the objective of determining the…

For the past century, humans have been increasingly dependent on plastics, but have not developed adequate disposal practices. In this lab, students are asked whether burning plastic for energy seems like a reasonable disposal technique. To answer the chemical aspects of this question, students use bomb calorimetry to quantify the combustion…

Nanoscale phenomena are under increasingly intense investigation both in academia and industry. The unique physical and chemical properties stemming from their high surface area and confined space lead to properties that are distinct from atomic and bulk materials. Students need experience in nanoscience to enter this growing field of nanoscience…

We present the use of an oxygen tolerant controlled radical polymerization (photoinduced electron/energy transfer-reversible addition fragmentation chain transfer polymerization, PET-RAFT) as a simple method for preparing controlled radical polymers in an undergraduate laboratory. Unlike conventional techniques, PET-RAFT polymerizations require no…

Exciting developments in the field of Green Chemistry spur the continuous innovation of experiments in the teaching laboratory. Beyond learning practical techniques, students can critically assess experiments using relevant metrics to propose further improvements and identify the most important interconnected impacts of these alternative products…

Dendrite growth affects material systems across applications as diverse as lithium batteries, organic light emitting diodes, turbine blades, and biological sensors. Their unique crystal structure and ability to physically see growth make for a unique undergraduate laboratory experience. This experiment uses dendrite growth to explore the physical…

Education reform calls for portraying science as a process of inquiry and argumentation grounded in the epistemic traditions of a domain. While experimentation is a core scientific investigation strategy, diverse approaches are represented across different domains of science. Ecosystem scientists use experiments as a core part of their…

Quantum mechanics is a field often considered very mathematical, abstract, and unintuitive. One way some instructors are hoping to help familiarize their students with these complex topics is to have the students see quantum effects in experiments in undergraduate instructional labs. Here, we present results from an interview study about what it…

Heterocyclic compounds are an integral part of research, particularly in the pharmaceutical field. The synthesis of such compounds in an undergraduate laboratory can help students understand the relevance and importance of their field of study. Our experimental activity introduces a novel procedure to synthesize coumarin, a heterocyclic formed by…

High-resolution mass spectrometry (HRMS) is an analytical technique that is typically used by mass spectrometry experts. However, with recent advancements, it is becoming more accessible to students in organic chemistry laboratories. Still, a significant knowledge gap exists between these experts and students. A straightforward laboratory…

The imine condensation reaction is commonly addressed in second semester organic chemistry classrooms as imines and their derivatives are found in many pharmaceutical scaffolds and biological and catalytic processes. Despite this, imine condensations are still absent from many organic chemistry laboratory curriculums. The work discussed here…

Nanozyme is a kind of mimetic enzyme possessing unique properties of nanomaterials and catalytic functions of natural enzymes. The nanozymes have the characteristics of high catalytic efficiency and good stability and are widely utilized in medicine, chemical industry, food, agriculture, and environment. This laboratory experiment is designed for…

The ability to solve geometric construction problems is justly regarded as an essential component of mathematical culture. The dynamic, general nature of objects provided by dynamic geometry systems allows the development of intuitive methods for solving construction problems. The core mathematical concept underlying this approach is the loci…