The purpose of this synthesis study was to assess the reliability and validity of the Draw-A-Scientist Test (DAST) and its variations across multiple studies, aiming to understand limitations and propose modifications for future application within and beyond the science domain. Given the existence of multiple DAST versions, this study quantified the frequency of validity threats across various DAST variations. Literature review results indicated that despite its widespread use, the DAST and its variations consistently encounter challenges related to construct validity and external validity. Additionally, this synthesis identified literature limitations in testing concurrent validity, predictive validity, and inter-rater reliability when applicable.