The tutorials of a second-year undergraduate organic chemistry course have been modified to include a retrosynthetic exercise in conjunction with a Molecule of the Week (MoW) challenge. In contrast to the original tutorial assignments in the course, which primarily focused on completing simple reaction roadmaps, the new tutorials place a heavier…

In 1827, Robert Brown noticed pollen suspended in water bouncing around erratically. It wasn't until 1905 that Albert Einstein provided an acceptable explanation of the phenomenon (Kac 1947): Brownian motion is the random movement of particles (e.g., pollen) in a fluid (liquid or gas) as a result of collisions with atoms and molecules. Movement of…

This study investigates students' conceptions of the carbon cycle with regard to the components they believe to be relevant to the carbon cycle, how they interrelate these components, the ways in which they trace carbon atoms, and the different levels of biological organisation they consider when doing so. A total of 142 students aged 13-16 years…

The purpose of the research was to understand the public's social Image of emerging technology-- nanotechnology. Furthermore, the differences among different major students and the decision-making style in "self-evaluation and other-evaluation" were analyzed too. In this research, the social image was defined by three phases,…

This two-period undergraduate laboratory experiment involves the synthesis of a mixture of isomeric unknowns, isolation of the mixture by means of distillation, and characterization of the two products primarily by NMR spectroscopy (1D and 2D) supported with IR spectroscopy and GC-MS techniques. Subsequent calculation and examination of the…

This lab experiment uses [superscript 31]P NMR spectroscopy of biomolecules to determine pK[subscript a] values and the binding energies of metal/biomolecule complexes. Solutions of adenosine nucleotides are prepared, and a series of [superscript 31]P NMR spectra are collected as a function of pH and in the absence and presence of magnesium or…

The increased availability of noncommercial 3D printers has provided instructors and students improved access to printing technology. However, printing complex ball-and-stick molecular structures faces distinct challenges, including the need for support structures that increase with molecular complexity. MolPrint3D is a software add-on for the…

The "Yet Another extended Hu¨ckel Molecular Orbital Package" (YAeHMOP) has been merged with the Avogadro open-source molecular editor and visualizer. It is now possible to perform YAeHMOP calculations directly from the Avogadro graphical user interface for materials that are periodic in one, two, or three dimensions, and to visualize…

Nonassociative learning is considered simple because it depends on presentation of a single stimulus, but it likely reflects complex molecular signaling. To advance understanding of the molecular mechanisms of one form of nonassociative learning, habituation, for ethologically relevant signals we examined song recognition learning in adult zebra…

The purpose of this study was to uncover pre-service science teachers' images and misconceptions regarding atomic orbital and self-ionization concepts. This study involved a total of 68 pre-service science teachers working at a public university during the 2015-2016 academic year. In this qualitative study, data were collated with the use of…

Spatial ability predicts success in STEM (Science, Technology, Education, and Mathematics) fields, particularly chemistry. This paper reports two studies investigating the unique contribution of mental rotation ability to spatial thinking in a STEM discipline. Using authentic disciplinary tasks from chemistry, we show that the difficulty of a…

Plasma protein binding measurements are an important aspect of pharmacology and drug development. Therefore, performing these measurements can provide a valuable and highly practical learning experience for students across many scientific disciplines. Here, we describe the design and characterization of a 3D-printed device capable of performing…

Introductory chemistry students encounter the concept of hybrid orbitals as a transition from atomic orbitals to molecular bonding. The principal purpose of learning hybridization in the undergraduate curriculum is to impart an understanding of the origins of molecular bonding and geometry. Physical models of both individual hybrid orbitals and…

Noncovalent interactions determine the three-dimensional structure of macromolecules and the binding interactions between molecules. Students struggle to understand noncovalent interactions and how they relate to structure-function relationships. Additionally, students' difficulties translating from two-dimensional representations to…

Clustered regularly interspaced short palindromic repeats (CRISPRs) represent a novel type of adaptive immune system found in eubacteria and archaebacteria. CRISPRs have recently generated a lot of attention due to their unique ability to catalog foreign nucleic acids, their ability to destroy foreign nucleic acids in a mechanism that shares some…