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Tsakanikos, Elias; Underwood, Lisa; Sturmey, Peter; Bouras, Nick; McCarthy, Jane – Research in Developmental Disabilities: A Multidisciplinary Journal, 2011
The present study employed the Disability Assessment Schedule (DAS) to assess problem behaviors in a large sample of adults with ID (N = 568) and evaluate the psychometric properties of this instrument. Although the DAS problem behaviors were found to be internally consistent (Cronbach's [alpha] = 0.87), item analysis revealed one weak item…
Descriptors: Measures (Individuals), Behavior Problems, Adults, Psychometrics
Tognin, Stefania; Viding, Essi; McCrory, Eamon J.; Taylor, Lauren; O'Donovan, Michael C.; McGuire, Philip; Mechelli, Andrea – Journal of Child Psychology and Psychiatry, 2011
Background: Schizophrenia is a neurodevelopmental disorder, and risk genes are thought to act through disruption of brain development. Several genetic studies have identified dystrobrevin-binding protein 1 (DTNBP1, also known as dysbindin) as a potential susceptibility gene for schizophrenia, but its impact on brain development is poorly…
Descriptors: Schizophrenia, Genetics, Brain, Child Development
Tousignant, Michel; Pouliot, Louise; Routhier, Danielle; Vrakas, Georgia; McGirr, Alexander; Turecki, Gustavo – Suicide and Life-Threatening Behavior, 2011
The first objective was to identify the provoking events of suicide in patients with schizophrenia or schizoid-type disorder, and to assess the humiliation component of these events. The second objective was to verify if quality of care during childhood is a vulnerability factor for suicide in patients with schizophrenia or schizoid-type…
Descriptors: Control Groups, Child Abuse, Aggression, Schizophrenia
Parker, Beth A.; Thompson, Paul D.; Jordan, Kathryn C.; Grimaldi, Adam S.; Assaf, Michal; Jagannathan, Kanchana; Pearlson, Godfrey D. – Research Quarterly for Exercise and Sport, 2011
The hippocampus is the primary site of memory and learning in the brain. Both normal aging and various disease pathologies (e.g., alcoholism, schizophrenia, and major depressive disorder) are associated with lower hippocampal volumes in humans and hippocampal atrophy predicts progression of Alzheimers disease. In animals, there is convincing…
Descriptors: Evidence, Exercise, Schizophrenia, Alzheimers Disease
Vitiello, Benedetto; Riddle, Mark A.; Yenokyan, Gayane; Axelson, David A.; Wagner, Karen D.; Joshi, Paramjit; Walkup, John T.; Luby, Joan; Birmaher, Boris; Ryan, Neal D.; Emslie, Graham; Robb, Adelaide; Tillman, Rebecca – Journal of the American Academy of Child & Adolescent Psychiatry, 2012
Objective: Both the diagnosis and treatment of bipolar disorder in youth remain the subject of debate. In the Treatment of Early Age Mania (TEAM) study, risperidone was more effective than lithium or divalproex in children diagnosed with bipolar mania and highly comorbid with attention-deficit/hyperactivity disorder (ADHD). We searched for…
Descriptors: Attention Deficit Hyperactivity Disorder, Obesity, Schizophrenia, Symptoms (Individual Disorders)
Sellbom, Martin; Bagby, R. Michael; Kushner, Shauna; Quilty, Lena C.; Ayearst, Lindsay E. – Assessment, 2012
In the current investigation, the authors examined the diagnostic construct validity of the "Minnesota Multiphasic Personality Inventory-2-Restructured Form" (MMPI-2-RF) in a patient sample. All participants were diagnosed via the "Structured Clinical Interview" for DSM-IV Axis I Disorders (SCID-I/P). The data set used in this…
Descriptors: Schizophrenia, Construct Validity, Clinical Diagnosis, Personality Traits
Burra, Tara A.; Hwang, Stephen W.; Rourke, Sean B.; Stergiopoulos, Vicky – International Journal of Mental Health and Addiction, 2012
This study examines differences in services available at the time of discharge for homeless and housed psychiatric inpatients. Participants diagnosed with schizophrenia or schizoaffective disorder were recruited from a general hospital psychiatric inpatient unit. Thirty homeless individuals and 21 housed controls (matched for diagnosis, gender,…
Descriptors: Social Services, Schizophrenia, Patients, Hospitals
Idol, Jacquelyn R.; Addington, Anjene M.; Long, Robert T.; Rapoport, Judith L.; Green, Eric D. – Journal of Autism and Developmental Disorders, 2008
We characterized a "t"(1;7)(p22;q21) reciprocal translocation in a patient with childhood-onset schizophrenia (COS) and autism using genome mapping and sequencing methods. Based on genomic maps of human chromosome 7 and fluorescence in situ hybridization (FISH) studies, we delimited the region of 7q21 harboring the translocation breakpoint to a…
Descriptors: Schizophrenia, Autism, Children, Genetics
Findling, Robert L.; Johnson, Jacqueline L.; McClellan, Jon; Frazier, Jean A.; Vitiello, Benedetto; Hamer, Robert M.; Lieberman, Jeffrey A.; Ritz, Louise; McNamara, Nora K.; Lingler, Jacqui; Hlastala, Stefanie; Pierson, Leslie; Puglia, Madeline; Maloney, Ann E.; Kaufman, Emily Michael; Noyes, Nancy; Sikich, Linmarie – Journal of the American Academy of Child & Adolescent Psychiatry, 2010
Objective: To examine the long-term safety and efficacy of three antipsychotics in early-onset schizophrenia spectrum disorders. Method: Patients (8 to 19 years old) who had improved during an 8-week, randomized, double-blind acute trial of olanzapine, risperidone, or molindone (plus benztropine) were eligible to continue on the same medication…
Descriptors: Maintenance, Safety, Schizophrenia, Drug Therapy
Ryan, J.; Woodyatt, G.; Copeland, D. – Journal of Intellectual Disability Research, 2010
Background: Knowledge of discourse abilities of adults with intellectual disability (ID) and mental illness is limited. The present study examined the procedural discourse skills of two cohorts of adults with ID--one cohort with (n = 7) and one cohort without (n = 7) a psychiatric diagnosis of psychosis. Methods: Participants completed the "dice…
Descriptors: Mental Retardation, Schizophrenia, Mental Disorders, Identification
Giusti, Laura; Mazza, Monica; Pollice, Rocco; Casacchia, Massimo; Roncone, Rita – Clinical Psychologist, 2013
Background: People with schizophrenia show impairments in metacognitive function, including awareness and monitoring of one's mental processes (Self-Reflectivity (SR)), recognition of the fallibility of one's thoughts, and the ability to infer others' emotions and intentions (Theory of Mind (ToM)). The aim of the present study was to explore…
Descriptors: Correlation, Theory of Mind, Metacognition, Schizophrenia
Gadow, Kenneth D.; DeVincent, Carla J. – Journal of Autism and Developmental Disorders, 2012
Children with autism spectrum disorder (ASD) with and without co-occurring schizophrenia spectrum traits (SST) were examined for differences in co-occurring psychiatric symptoms, background characteristics, and mental health risk factors. Participating mothers and teachers completed a DSM-IV-referenced rating scale and a background questionnaire…
Descriptors: Rating Scales, Mental Health, Autism, Schizophrenia
Murrell, Amy R.; Scherbarth, Andrew J. – International Journal of Behavioral Consultation and Therapy, 2011
Acceptance and Commitment Therapy (ACT; Hayes, Strosahl, & Wilson, 1999) has been found effective in treating a wide number of psychological conditions affecting adults. To date, however, little research has been done on the use of ACT with youth and parents. Few efforts have been made at summarizing the literature that does exist. This article,…
Descriptors: Psychotherapy, Behavior Modification, Children, Adolescents
Chaplin, Eddie; Gilvarry, Catherine; Tsakanikos, Elias – Research in Developmental Disabilities: A Multidisciplinary Journal, 2011
There is very limited evidence on the patterns of recreational substance use among adults with Intellectual Disabilities (ID) who have co-morbid mental health problems. In this study we collected clinical and socio-demographic information as well as data on substance use patterns for consecutive new referrals (N = 115) to specialist mental health…
Descriptors: Health Services, Marijuana, Mental Retardation, Schizophrenia
Beaudet, Arthur L. – Child Development, 2013
Chromosomal microarray analysis (CMA) has emerged as a powerful new tool to identify genomic abnormalities associated with a wide range of developmental disabilities including congenital malformations, cognitive impairment, and behavioral abnormalities. CMA includes array comparative genomic hybridization (CGH) and single nucleotide polymorphism…
Descriptors: Genetics, Genetic Disorders, Developmental Disabilities, Identification