In study of hospitalized suicidal youth, account of 16-year-old girl, diagnosed as schizophrenic, is analyzed to gain insight into family's role in suicidal career of adolescent preoccupied with death and dying, sleep, and drugs; the interplay of her construction of reality with her risk-taking, self-injurious way of life; and her perceived…

Reports on two studies in which college students rated the degree to which clients were responsible for causing and solving their problems. Study 1 revealed that men held male clients responsible for problems. Study 2 demonstrated that clients with schizophrenia were evaluated differently than those with problems of anxiety and personal…

Objective: To examine the development of first-onset major depressive disorder (MDD) in children at high and low familial risk for depression in a prospective study. Method: High-risk children (n = 76) who were free of any lifetime affective disorder and had at least one first-degree and one second-degree relative with a lifetime history of…

Objective: To assess the feasibility and effectiveness of an evidence-based pharmacotherapy algorithm in the treatment of pediatric bipolar disorder. Method: The study reports the results of a study of 64 bipolar type I subjects who were treated according to an algorithm developed in our specialty clinic. All subjects had been diagnosed using the…

Objective: To retrospectively examine rates of hematological adverse events (HAEs) in psychiatrically ill, hospitalized children treated with clozapine. Method: Clozapine treatment was administered in an open-label fashion using a flexible titration schedule, and data from weekly complete blood counts was obtained. The rate of neutropenia and…

This paper examines methodological challenges inherent in conducting research on families of children with autism and in comparing these families with others who are coping with different types of disabilities or who have nondisabled children. Although most comparative research has contrasted families whose child has autism with those whose child…

Asperger syndrome (AS) is a childhood-onset disorder often described as a mild variant of autism. Although classified as a distinct disorder in the DSM-IV, its overlap with autism continues to be a matter of ongoing debate. While the family genetic origins of autism are well established, few studies have investigated this topic in AS using current…

In this study we investigated the putative role of cognitive dysfunction, diagnosis (schizoaffective versus schizophrenia disorder), and alcoholism as risk factors for suicidal behavior among individuals with DSM-IV schizophrenia or schizoaffective disorders. Subjects received cognitive tests and medical records were reviewed for evidence of a…

This review focuses on empirical studies with pre- and post-test measures of functioning that have attempted to assess the benefits of psychotherapy with schizophrenics. The first part of the review concentrates on various subgroups of schizophrenia, which appear to be influenced by subject variables and manifest clinical symptomatology. The…

Childhood schizophrenia is a rare but serious disorder with complex symptoms that affect children and their families. Childhood schizophrenia was once the term applied for all childhood psychoses, including autism and mood disorders, but more recently researchers have distinguished childhood schizophrenia from other disorders. There are differing…

The present study explored a method of altering the reinforcing properties of the verbal event good in chronic, process, nonparanoid schizophrenics. When good was repeatedly paired with the termination of censure in the reaction time task, it became an effective reinforcer on a subsequent verbal conditioning task. (Author)

Recent research suggests that family attitudes may be significant determinants of relapse and hospital readmission among both schizophrenics and hospitalized depressives. To assess the incremental effectiveness of inpatient family intervention within the context of treatment for schizophrenic disorder and major affective disorder patients, a…

Paper prepared, in part, within the framework of activities supported by the Veterans Administration Program Evaluation Staff.

Study financed by Research Grant M-6167 from the National Institute of Mental Health, U.S. Public Health Service.

In this study of young male schizophrenic patients who reported they were not taking antipsychotic medication at follow-up, those treated with placebos in contrast to those treated with chlorpromazine while hospitalized showed significantly greater long term clinical improvement, less pathology at follow-up, fewer rehospitalizations and better…