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Goldstein, Benjamin I.; Shamseddeen, Wael; Spirito, Anthony; Emslie, Graham; Clarke, Greg; Wagner, Karen Dineen; Asarnow, Joan Rosenbaum; Vitiello, Benedetto; Ryan, Neal; Birmaher, Boris; Mayes, Taryn; Onorato, Matthew; Zelazny, Jamie; Brent, David A. – Journal of the American Academy of Child & Adolescent Psychiatry, 2009
Objective: Despite the known association between substance use disorders and major depressive disorder (MDD) among adolescents, little is known regarding substance use among adolescents with MDD. Method: Youths with MDD who had not improved after an adequate selective serotonin reuptake inhibitor trial (N = 334) were enrolled in the Treatment of…
Descriptors: Sexual Abuse, Schizophrenia, Drug Use, Suicide
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Toplak, Maggie E.; Pitch, Ashley; Flora, David B.; Iwenofu, Linda; Ghelani, Karen; Jain, Umesh; Tannock, Rosemary – Journal of Abnormal Child Psychology, 2009
To examine the unity and diversity of inattention and hyperactivity/impulsivity symptom domains of Attention-Deficit/Hyperactivity Disorder (ADHD) in a clinical sample of adolescents with ADHD. Parents and adolescents were administered a semi-structured diagnostic interview, the Schedule for Affective Disorders and Schizophrenia for School-Age…
Descriptors: Conceptual Tempo, Schizophrenia, Hyperactivity, Attention Deficit Disorders
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Tully, Phillip J.; Edwards, Christopher J. – Clinical Psychologist, 2009
This case study reports the outcomes of cognitive therapy for social anxiety in a 45-year-old man with a 27-year history of paranoid schizophrenia. The intervention targeted the overlapping and interrelated symptoms of social anxiety and delusional beliefs. After 11 sessions of treatment, the patient showed no improvement in social anxiety,…
Descriptors: Schizophrenia, Cognitive Restructuring, Therapy, Anxiety
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Schirmbeck, Frederike; Georgi, Alexander; Strohmaier, Jana; Schmael, Christine; Boesshenz, Katja V.; Muhleisen, Thomas W.; Herms, Stefan; Hoffmann, Per; Jamra, Rami Abou; Schumacher, Johannes; Maier, Wolfgang; Propping, Peter; Nothen, Markus M.; Cichon, Sven; Rietschel, Marcella; Schulze, Thomas G. – Journal of Autism and Developmental Disorders, 2008
Whereas "Dysbindin" is considered a schizophrenia vulnerability gene, there is no consistency of findings. Phenotype refinement approaches may help to increase the genetic homogeneity and thus reconcile conflicting results. Premorbid adjustment (PMA) has been suggested to aid the phenotypic dissection. Gornick et al. ("J Autism Dev…
Descriptors: Schizophrenia, Patients, Genetics, Foreign Countries
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Kumra, Sanjiv – Journal of the American Academy of Child & Adolescent Psychiatry, 2008
The article describes the use of structural neuroimaging to understand the psychopathology of childhood-onset schizophrenia. Results showed an increase in lateral volumes, reduced total and regional volumes of gray matter in the cortex and increased basal ganglia volumes as in adult-onset schizophrenia in comparison with healthy subjects.
Descriptors: Psychopathology, Schizophrenia, Diagnostic Tests, Brain
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Penttila, Jani; Paillere-Martinot, Marie-Laure; Martinot, Jean-Luc; Mangin, Jean-Francois; Burke, Lisa; Corrigall, Richard; Frangou, Sophia; Cachia, Arnaud – Journal of the American Academy of Child & Adolescent Psychiatry, 2008
Disturbances in the temporal lobes and alterations in cortical folding in adult on-set schizophrenia are studied using magnetic resonance T1 images of 51 patients. The study showed that patients with early on-set schizophrenia had lower global sulcal indices in both hemispheres and the left collateral sulcus has a lower sulcal index irrespective…
Descriptors: Schizophrenia, Physics, Patients, Brain
Lattari, Fallon; Dragowski, Eliza A. – Communique, 2011
Childhood-onset schizophrenia is an exceedingly rare mental illness whose complex, multifaceted behavioral presentation can disrupt child development and raise diagnostic and treatment difficulties for attending clinicians. The disorder, affecting one in 30,000 children, shares the same diagnostic criteria and symptoms as its adult counterpart,…
Descriptors: Schizophrenia, Symptoms (Individual Disorders), Child Development, At Risk Persons
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Beecher, Blake – Journal of Family Social Work, 2009
Family involvement has been identified as a best practice in the treatment of schizophrenia. Yet studies show a small number of families of individuals with schizophrenia are involved in treatment. In this mixed method study, community mental health practitioners from different disciplines responded to a quantitative survey (N = 88), a qualitative…
Descriptors: Schizophrenia, Family Attitudes, Family Involvement, Mental Health
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Rockers, K.; Ousley, O.; Sutton, T.; Schoenberg, E.; Coleman, K.; Walker, E.; Cubells, J. F. – Journal of Intellectual Disability Research, 2009
Background: Approximately one-third of individuals with 22q11.2 deletion syndrome (22q11DS), a common genetic disorder highly associated with intellectual disabilities, may develop schizophrenia, likely preceded by a mild to moderate cognitive decline. Methods: We examined adolescents and young adults with 22q11DS for the presence of executive…
Descriptors: Genetic Disorders, Mental Retardation, Schizophrenia, Psychopathology
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Carroll, Christine A.; O'Donnell, Brian F.; Shekhar, Anantha; Hetrick, William P. – Brain and Cognition, 2009
Schizophrenia may be associated with a fundamental disturbance in the temporal coordination of information processing in the brain, leading to classic symptoms of schizophrenia such as thought disorder and disorganized and contextually inappropriate behavior. However, the majority of studies that have examined timing behavior in schizophrenia have…
Descriptors: Schizophrenia, Time Management, Cognitive Processes, Brain
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Prasad, Sarah E.; Howley, Sarah; Murphy, Kieran C. – Developmental Disabilities Research Reviews, 2008
There is an overwhelming evidence that children and adults with 22q11.2 deletion syndrome (22q11.2DS) have a characteristic behavioral phenotype. In particular, there is a growing body of evidence that indicates an unequivocal association between 22q11.2DS and schizophrenia, especially in adulthood. Deletion of 22q11.2 is the third highest risk…
Descriptors: Mental Disorders, Schizophrenia, Pathology, Genetic Disorders
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O'Driscoll, Gillian A.; Callahan, Brandy L. – Brain and Cognition, 2008
Abnormal smooth pursuit eye-tracking is one of the most replicated deficits in the psychophysiological literature in schizophrenia [Levy, D. L., Holzman, P. S., Matthysse, S., & Mendell, N. R. (1993). "Eye tracking dysfunction and schizophrenia: A critical perspective." "Schizophrenia Bulletin, 19", 461-505]. We used meta-analytic procedures to…
Descriptors: Maintenance, Schizophrenia, Patients, Effect Size
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Ran, Mao-Sheng; Chan, Cecilia Lai-Wan; Chen, Eric Yu-Hai; Tang, Cui-Ping; Lin, Fu-Rong; Li, Li; Li, Si-Gan; Mao, Wen-Jun; Hu, Shi-Hui; Schwab, Gerhard; Conwell, Yeates – Suicide and Life-Threatening Behavior, 2008
Little is known about the differences in mortality among non-institutionalized geriatric and younger patients with schizophrenia. In this study long-term mortality and suicidal behavior of all the geriatric (age greater than or equal to 65 years), middle-age (age 41-64 years), and young (age 15-40 years) subjects with schizophrenia living in a…
Descriptors: Schizophrenia, Suicide, Death, Mortality Rate
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Sarrett, Jennifer C.; Kushner, Howard I. – Annals of Science, 2011
Watters questions the universality of mental illness and warns of the harms that accompany the exportation of Western typologies to non-Western cultures. He is particularly concerned that these effects will be exacerbated by the upcoming revisions of the "Diagnostic and Statistical Manual of Mental Disorders" ("DSM-V").…
Descriptors: Mental Disorders, Mental Health, Autism, Global Approach
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Lysaker, Paul H.; Tsai, Jack; Hammoud, Kristin; Davis, Louanne W. – International Journal of Behavioral Consultation and Therapy, 2009
Maladaptive styles of coping are believed to be a barrier to recovery from schizophrenia. In this study we obtained measures of coping for 133 persons with schizophrenia or schizoaffective disorder. A cluster analysis was then performed based on those scores and produced five distinctive coping profiles. These five groups were then compared on…
Descriptors: Schizophrenia, Coping, Multivariate Analysis, Profiles
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