ERIC Number: EJ1444412
Record Type: Journal
Publication Date: 2023-Sep
Pages: 7
Abstractor: As Provided
ISBN: N/A
ISSN: ISSN-0021-9584
EISSN: EISSN-1938-1328
Eutectics in Pharmacy Curriculum: A Simple Demonstration with Pharmaceutical Relevance
Anis Daou; Shijimol M. Arakkal; Alaaldin M. Alkilany
Journal of Chemical Education, v100 n9 p3533-3539 2023
In chemistry, a eutectic mixture refers to a mixture of two or more components at which the lowest possible freezing point is observed. This phenomenon is covered in a wide range of curricula such as physics, chemistry, chemical engineering, and pharmacy to various depths. Despite the significance of this phenomenon in pharmaceutical compounding and formulation, standard pharmacy curricula provide only limited coverage of the eutectic mixture and the theoretical aspects associated with its phase diagram. A practical session on a eutectic mixture should augment the theoretical pedagogical component and enable amore profound understanding. Despite the existence of educational publications that discuss this phenomenon from a chemical perspective, there is currently no reported experimental laboratory specifically focused on the eutectic phenomenon and its implications in the field of pharmacy. In this study, we employ camphor and menthol as pharmaceutical active ingredients that illustrate a robust eutectic phenomenon within practical temperature ranges. Moreover, we utilize the eutectic phenomenon and the resulting liquefaction effect upon mixing camphor and menthol to prepare semisolid pharmaceutical dosage forms (gels and rubs),demonstrating to students the impact of this phenomenon in drug compounding and formulation.
Descriptors: Pharmaceutical Education, Chemistry, Science Instruction, Science Curriculum, Theory Practice Relationship, Pharmacy, Teaching Methods, Science Experiments
Division of Chemical Education, Inc. and ACS Publications Division of the American Chemical Society. 1155 Sixteenth Street NW, Washington, DC 20036. Tel: 800-227-5558; Tel: 202-872-4600; e-mail: eic@jce.acs.org; Web site: http://pubs.acs.org/jchemeduc
Publication Type: Journal Articles; Reports - Evaluative
Education Level: Higher Education; Postsecondary Education
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A
Grant or Contract Numbers: N/A