We illustrate how to analyze complete generalizability theory (GT) designs using structural equation modeling software ("lavaan" in R), compare results to those obtained from numerous ANOVA-based packages, and apply those results in practical ways using data obtained from a large sample of respondents, who completed the Self-Perception Profile for College Students (Neemann & Harter, 2012) on two occasions. Results revealed that estimates of variance components, generalizability coefficients, dependability coefficients, and proportions of measurement error derived from "lavaan" were essentially equivalent to those produced by the GT packages GENOVA and "gtheory" in R and variance component programs in SPSS, SAS, and R. Within the article and extended online Supplemental Material, we illustrate how indices obtained from these resources can be used for either norm- and criterion-referencing purposes and for estimating effects of changes made to measurement procedures. We further describe ways to use structural equation models for applications of GT beyond what conventional ANOVA-based packages would typically permit.