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Wenyu Lai; Baolin Li – Journal of Chemical Education, 2025
Paal--Knorr reactions are a classical method for synthesizing pyrroles, using 1,4-dicarbonyl compound and amine as reactants. It has the characteristics of green chemistry, as only two molecules of water are lost. In this teaching and learning experiment, 2,5-hexanedione and 4-"tert"-butylaniline were used to synthesize…
Descriptors: Organic Chemistry, College Science, Environmental Education, Science Curriculum
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Ângelo Luís; Fernanda Domingues – Biochemistry and Molecular Biology Education, 2025
Bacteria have developed a cell-to-cell communication system called quorum sensing (QS), allowing them to regulate group behavior and synchronize the expression of virulence factors, responsible for increasing their infection capacity and resistance to antimicrobials. Although the control of microbial infections through the inhibition of microbial…
Descriptors: Inhibition, Evaluation Methods, Science Experiments, Microbiology
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Li, Yunhua; Chen, Cuixue; Ye, Meiling; Imbault, Alexander Luis – Journal of Chemical Education, 2022
Organizing undergraduates in chemistry, energy engineering, and chemical engineering specialties to participate in an energy transformation experiment can encourage them to think about the impact of human activities on nature and stimulate them to learn more about the topic. This laboratory experiment demonstrates a general approach to the…
Descriptors: Hands on Science, Fuels, Energy, Chemical Engineering
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Benjamin Po¨lloth; Hannah Ro¨hrig; Stefan Schwarzer – Journal of Chemical Education, 2022
Lateral flow assays play a key role in mass testing for COVID-19, for example, in schools. The red color of the detection lines is caused by gold nanoparticles that are conjugated to antibodies. Hence, these tests present a very topical learning opportunity in the emerging field of nanoscience. To highlight the role of gold nanoparticles, a…
Descriptors: High School Students, Science Experiments, Chemistry, Science Activities
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Michelle Lee; Nathan J. Vosburg; Emily A. Shimizu; Manuel A. Renteri´a-Go´mez; Roci´o Ga´mez-Montan~o; David A. Vosburg – Journal of Chemical Education, 2022
A new undergraduate organic laboratory experiment has been developed and implemented for the Ugi three-component synthesis of the topical anesthetic lidocaine with excellent atom economy. Paraformaldehyde, diethylamine, and 2,6-dimethylphenyl isocyanide were combined and conveniently stirred at room temperature for a week in methanol with acetic…
Descriptors: Undergraduate Study, Organic Chemistry, Laboratory Experiments, Climate
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Bingxing Wang; Qi Wang; Xiaoying Jiang; Yu Zhang; Yongcai Zhang; Yuping Zhang – Journal of Chemical Education, 2022
Mercury beating heart (MBH) is a well-known demonstration of redox processes. However, the development and application of the MBH system are significantly restricted due to its safety issues. Here, a direct current electric field-enabled gallium-based liquid metal heartbeat in a salt solution or alkaline solution is introduced as a demonstration…
Descriptors: Chemistry, Undergraduate Study, Metallurgy, Science Laboratories
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Sydney Demers; Joshua Fung-A-Fat; Jeremy Andreatta; Margaret E. Kerr; Weichu Xu – Journal of Chemical Education, 2022
Undergraduate organic chemistry laboratory courses act as a baseline for introductory scientific experimentation. These courses provide students with the knowledge and skills for their future careers. The traditional lab is conducted by providing a structured protocol of the experiment for the students to follow and reproduce the assigned task…
Descriptors: Student Research, Student Interests, Undergraduate Students, Organic Chemistry
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Oliver W. M. Baldwin; Linden H. Conrad-Marut; Gregory L. Beutner; David A. Vosburg – Journal of Chemical Education, 2022
A new undergraduate organic laboratory experiment has been developed for amide bond formation between biorenewable 2-furoic acid and either of two substituted piperazines to prepare medicinally relevant amide products using a procedure with industrial significance. The reactions proceeded smoothly under ambient conditions using the combination of…
Descriptors: Undergraduate Study, Organic Chemistry, Science Laboratories, Laboratory Experiments
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Yasuda, Keita – Journal of Chemical Education, 2021
A laboratory experiment was performed using tetra-n-butylammonium bromide (TBAB) ionic semiclathrate hydrate, a crystalline compound. Ionic semiclathrate hydrates have unique properties, and hence, novel technologies utilizing the ionic semiclathrate hydrates have been proposed to date. Thus, students could learn fundamentals of functional…
Descriptors: Laboratory Experiments, Science Experiments, Chemistry, Science Instruction
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Lucas, Danielle R.; Bressiani, Thaiany S. C.; Gomes, Anne C. C.; Hayashide, Ingrid M.; Simas, Naomi K.; Lelis, Maria F. F.; Kuster, Ricardo M.; Moura, Paulo R. G. – Journal of Chemical Education, 2021
A laboratory experiment was developed to introduce undergraduate chemistry students to the chemical characterization of agroindustrial waste extracts by gas chromatography-mass spectrometry (GC--MS). The students prepared hexane and dichloromethane extracts from black pepper ("Piper nigrum" L.) waste. GC--MS analysis revealed the…
Descriptors: Chemistry, Undergraduate Students, Science Experiments, Laboratory Experiments
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Oh, Pil-Kwang; Kang, Seong-Joo – Journal of Chemical Education, 2021
Artificial intelligence (AI) is receiving a lot of attention in various fields. There is a need for educating students in AI technology. In this context, we have created a new type of carbon dioxide fountain by integrating AI with the well-established Arduino-carbon dioxide fountain experiment. This experiment consists of an Arduino…
Descriptors: Artificial Intelligence, Chemistry, Science Experiments, Science Instruction
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Miller, William J. W.; Torres-Ruedas, Kelin; Waxman, Sophia M.; Allen, Dale; Turman, Josh; Bartholomew, Autumn Jackson – Journal of Chemical Education, 2021
A handheld refractometer (HHR) is a versatile instrument in the chemistry lab or in the workplace. It is also inexpensive enough (<$25 U.S.) that all students in a chemistry lab can have one or students completing laboratories remotely can purchase one. We report four applications of two different HHRs: one HHR for which the scale reads…
Descriptors: Chemistry, Science Instruction, Science Laboratories, Laboratory Equipment
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Laguta, Anna N.; Eltsov, Sergey V.; Mchedlov-Petrossyan, Nikolay O. – Journal of Chemical Education, 2021
This experimental lab set is for students taking college chemistry courses. It includes four laboratory works and completely illustrates the important parts of chemical kinetics, namely the determination of the rate constant and the determination of the factors influencing its value. They can be used in a laboratory set for a physical chemistry…
Descriptors: Chemistry, Kinetics, College Science, Science Instruction
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Abby L. Manning; Bryanna N. Roos; Amber Flynn Charlebois; Kelly Hutchinson-Anderson; Stephen G. Tajc – Journal of Chemical Education, 2023
In an effort to further develop critical thinking and problem solving skills, a guided-inquiry-based, multioutcome organic chemistry synthesis and characterization experiment was developed. Students were provided with the protocol for a time-saving microwave-assisted acetanilide synthesis reaction from acetic anhydride and an unknown primary aryl…
Descriptors: Active Learning, Inquiry, Organic Chemistry, Laboratory Experiments
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Tiano, Martin – Journal of Chemical Education, 2020
We adapted a classical asymmetric Michael addition for a 1 day experimental session (6-8 h) for third- or fourth-year undergraduate students. The experiment contains three steps: synthesis of a chiral Lewis acid, LiAl((S)-BINOL)[subscript 2], then its use as a catalyst in the Michael addition of diethyl malonate on cyclopentenone, followed by…
Descriptors: Undergraduate Students, Chemistry, Science Experiments, Laboratory Experiments
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