Education leaders in Nebraska and South Dakota partnered with the Regional Educational Laboratory Central to examine how completing a sequence of career and technical education (CTE) courses in high school affects students' rates of on-time high school graduation and their rates of postsecondary education enrollment and completion within two and five years. The study found that CTE concentrators (students who complete a sequence of CTE courses aligned to a specific career field such as manufacturing or education and training) were 7 percentage points more likely than non-CTE concentrators to graduate from high school on time and 10 percentage points more likely to enroll in any type of postsecondary education within two years of their expected high school graduation year. The study also found that CTE concentrators were 3 percentage points more likely than non-CTE concentrators to earn a postsecondary award, such as a professional certificate, diploma, or associate's or bachelor's degree, within five years of their expected high school graduation year. CTE concentrators were 4 percentage points more likely than non-CTE concentrators to obtain up to an associate's degree as their highest postsecondary award within five years of their expected high school graduation year but 1 percentage point less likely to obtain a bachelor's degree or higher. [For the appendixes, see ED612631; for the study brief, see ED612632; for the study snapshot, see ED612633.]