The Science Notebook in a Universal Design for Learning Environment (SNUDLE) is a digital notebook that uses the Universal Design for Learning framework to support active science learning among elementary school students, particularly those who struggle with reading and writing or are unmotivated to learn science. Preliminary findings from the first of a two-year randomized control trial suggest no significant impact on motivation or academic achievement in science among the full sample of fourth graders receiving the SNUDLE intervention. Moderator analysis indicates significant positive interaction effects of the intervention on motivation in science and science content assessments among students with learning disabilities.