Margaret Sanger was a crusader for female reproductive rights. Thanks to her tireless efforts, not only are contraceptives now legal, women can also control the size of their families, a basic right denied them until the 1960s. Throughout the better part of the twentieth century Sanger faced public outcry and even arrest in her campaign to make contraceptives known and legal for women around the world. In her lifelong quest, Margaret Sanger demonstrated impeccable leadership and brought about a tremendous legacy as she fought for women's reproductive rights. This article describes the leadership and legacy she has left through her crusade by providing a history of her life.