We herein report an efficient aerobic oxidative cleavage of meso-hydrobenzoin to benzaldehyde using a heterogeneous earth-abundant metal oxide catalyst. The reaction can be carried out at 70 °C in ethanol and uses a balloon filled with O2 as oxidant. Reagents are simple and have long shelf lives, and the whole laboratory exercise can be done in…

Biomedical engineering (BME) is a multidisciplinary, constantly advancing field; as such, undergraduate programs in BME must continually adapt. Elective courses provide opportunities for students to select topic areas relevant to their interests or future careers. Specifically, laboratory courses allow experiential learning in specialized topics…

In analytical chemistry, discussing different method sand techniques of analysis is essential to promote critical thinking and reasoning. Analytical courses in the chemist, pharmacist, and biochemist curricula represent the opportunity to study concepts such as experimental design, sampling, development, and optimization of protocols, data…

The prompt introduction of single-molecule science into undergraduates' curricula is an urgent but challenging task. However, the research experiments are often too complicated and the instruments are too expensive to be widely transferred into a compulsory course of undergraduate students. Herein, we introduce a recently developed nanopore…

Reorienting organic chemistry laboratories with an emphasis on systemic thinking can only be beneficial to students. Addressing the challenges of climate change and the development of renewable resources with a fundamental reaction, such as the hydrogenation of an alkene, will allow students to see organic chemistry as a science beneficial to…

Undergraduate laboratory courses, owing to their larger sizes and shorter time slots, are often conducted in highly structured modes. However, this approach is known to interfere with students' engagement in the experiments. To enhance students' engagement, we propose an alternative mode of running laboratory courses by creating some…

We developed a multipart laboratory experiment on the synthesis of free-standing hydrogels for junior to senior undergraduate students. In this experiment series that runs over the course of multiple 3-h lab periods, small everyday objects belonging to the students are reproduced as hydrogels by first creating negative templates in thermally cured…

The advanced organic chemistry experiments describe the preparation of fused six-membered lactams to isoxazole and isoxazoline by employing Ugi four-component reaction (U-4CR) and intramolecular nitrile oxide cyclization (INOC) synthetic sequence. The experiments were carried out in 28 h (overnight for U-4CR) and 2 h (for INOC) using commercially…

In the first-year general chemistry laboratory course, instrumental data collection involving sample quantification has often been limited to absorption spectroscopy due to the inaccessibility of emission techniques suitable for large enrollments and novice users. In this laboratory experiment, students explore the complementary techniques of…

Understanding the controls of the oxidation rate of iron (Fe) in oxygenated aquatic systems is fundamental for students of the Earth and Environmental Sciences as it defines the bioavailability of Fe, a trace metal essential for life. The laboratory experiment presented here was successfully developed and used during a third-year undergraduate lab…

Zinc oxide is a common additive in food, cosmetics, and medicines. Here, we describe the validation of methods to analyze two pharmaceutical samples containing ZnO--talc powder and dermal ointment--by ethylenediaminetetraacetic acid (EDTA) titration. The methods developed were implemented as a practical class to students of a Quantitative Analysis…

This paper presents an experimental lab designed for undergraduate students which focuses on soil science and chemistry. Students perform a series of tests to classify soil's phosphate retaining characteristics, texture, pH, organic matter content, and permeability with the addition of a novel soil amendment, Al Mg biochar. This lab has minimal…

The carbonyl group of an aldehyde or ketone reacts with different types of nucleophiles through a nucleophilic addition reaction. When the nucleophile is water, the product obtained is a "gem"-diol or geminal diol. This functionalization is unstable and quickly reverts to the parent carbonyl group. The chemistry of "gem"-diols…

A [beta]-lactam, the core structure unit of clinically important antibiotics such as penicillin and cephalosporin, is one of the most commonly encountered four-membered heterocycles in organic chemistry and is widely used in medicine and biochemistry. The Kinugasa reaction, a copper­(I)-catalyzed cycloaddition of a terminal alkyne with a nitrone,…

The Leidenfrost nanochemistry synthesis of gold colloids was introduced in this "Journal" as an advanced method to synthesize gold nanoparticles during an undergraduate nanochemistry research project. When trying to repeat these experiments in the laboratory, we experienced difficulties in the synthesis of the gold nanoparticles since…