The purposes of the study were 1) to investigate the effectiveness of integrated brain-based learning and skills training on grade 11 students' learning achievement in linear and quadratic functions 2) to compare the achievement of grade 11 students before and after using integrated brain-based learning and skills training, and 3) to study students' satisfaction with the integrated brain-based learning and skills training. The participants were 40 grade 11 students in a Thai public school selected by the cluster sampling method. Research instruments were 1) a learning management plan 2) skills training 3) a learning Achievement Test, and 4) a Satisfaction Questionnaire. Statistics used in data analysis were percentage, average, standard deviation, and paired samples t-test. The results of the study indicate that 1) the effectiveness of the integrated brain-based learning and skills training on grade 11 students' learning achievement in linear and quadratic functions, 2) the achievement on grade 11 students after learning with the learning management was significantly higher than before using the treatmen, and 3) students was satisfied with the learning processes during the implementation of the learning management plan. The result of the study contributes to the area of mathematics education as it presents an alternative instructional method that combines the benefits of teaching principles to teach a complicated concept in mathematics. Moreover, it illustrates how the two principles are integrated to form a learning management plan that could drive learners' learning process.