The research was conducted to examine whether the implementation of Collaborative Strategic Reading (CSR) was effective to enhance students' reading comprehension viewed from self-efficacy. This research was a quasi-experimental design, which consisted of 60 senior high school students in the eastern part of Indonesia, specifically Lombok. The participants were selected by purposive sampling technique, the participants were divided into two groups: the experimental group taught by CSR as the treatment, and the control group taught by the previous teacher's strategy that was Student Team Learning (STL). To obtain the data of this research, the instruments used were 25 items of reading comprehension based on the indicators of reading and 25 questionnaires used the likert scale test to see the level of self-efficacy of the participants. Furthermore, a two-way ANOVA and descriptive test were used to analyze the data. Finally, the results showed that Collaborative Strategic Reading (CSR) was significantly effective to improve students' reading comprehension. In addition, there was an interaction between teaching strategy and self-efficacy towards students' reading comprehension. [For the full proceedings, see ED652261.]