Reducing the carbon footprint of higher education institutions has become a global trend in recent years, as they are the axis of society's scientific and technological transformation that must be carried out with a sustainable approach. Among the many approaches that can contribute to this problem are the digital transformation of academic and administrative processes and its impact on reducing paper use. This study details the statistical analysis of the digital transformation process based on the modules and computer services implemented by the ICT department in a higher education institution and its incidence in reducing the use of paper by its teaching and administrative staff. For this purpose, an initial instrument was proposed, consisting of 18 ordinal, three categorical and two numerical variables. After applying statistical data processing and validation techniques, it was reduced to 13 ordinal variables, three categorical and two influential numerical variables. In addition, this study has proposed an appropriate statistical protocol for the design and extraction of information applicable in the context of higher education institutions, consisting of the techniques: Mahalanobis distances, confirmatory factor analysis, Kruskal-Wallis, Mann-Whitney's U and Wilcoxon tests. The results showed the power of confirmatory factor analysis as a technique for obtaining models to measure indirectly observed latent variables, such as perceptions of digital transformation and paper reduction. In addition, it was found that the modules, systems, and computer tools implemented in the institution significantly reduced the execution times for performing administrative and teaching tasks in the institution, and significant differences were identified in the perception of digital transformation and reduction of paper use among staff.