This study investigated the relationship among academic self-concept, social support, and college adjustment of first-year college students enrolling at a Hispanic Serving Institution in the southwestern United States. A total of 496 first-year undergraduate students (291 females, 205 males) participated in the study. Results indicated that being multiracial had the most effect in adjustment, compared to being African American, Hispanic, and White. One of the factors affecting success in educational institutions is academic self-concept. Based on the results of our regression analysis, we found that social support, academic adjustment, and attachment were statistically significant predictors of academic self-concept.