The challenges state education agencies (SEAs) must address are exceedingly complex, requiring sophisticated levels of thinking and problem-solving as well as the ability to leverage disparate points of view in finding impactful solutions. These challenges are technical, requiring specific and known solutions to achieve desired results. To provide more coherent, integrated services to the field in the face of complex challenges, SEAs need to engage in systems change. This brief from the Region 15 Comprehensive Center shares its iterative Systems Review approach that assists SEAs in considering new and more effective ways to build coherence, increase efficiency, and improve workflow--all in the service of effectively supporting local education agencies (LEAs) in implementing state priorities.