The carbonyl group of an aldehyde or ketone reacts with different types of nucleophiles through a nucleophilic addition reaction. When the nucleophile is water, the product obtained is a "gem"-diol or geminal diol. This functionalization is unstable and quickly reverts to the parent carbonyl group. The chemistry of "gem"-diols…

A laboratory experiment was designed to provide students with an introduction to byproduct valorization by producing an analogue of biodiesel (fatty acid ethyl esters, FAEE) via lipid extraction and subsequent transesterification from spent coffee grounds (SCG). Valorization is the process of upgrading underutilized or discarded wastes or…

This laboratory experiment consists of the synthesis of two series of alkaline-earth titanates (calcium-strontium and strontium-barium)to corroborate Vegard's law by obtaining their X-ray diffraction patterns and plotting the lattice parameter versus mole fraction of both cations. This experiment allows students to understand the key concepts in…

An upper-division undergraduate- or graduate-level laboratory experiment, challenging students to identify bovine serum albumin, equine myoglobin, bovine calmodulin, and bovine cytochrome c, uses four methods of matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS): linear positive, in-source decay, peptide…

The principles of process-oriented guided inquiry learning (POGIL) are applied to the analysis of the emission spectrum of atomic hydrogen. Over the course of three learning cycles, students construct the hydrogen atom's energy level diagram and assign quantum numbers using their measurements of the Balmer series plus additional information on the…

Green chemistry is finding its place as one of the most essential study topics in the curriculum of future chemists and chemical engineers. Experiments that meet green chemistry principles contribute to make the laboratory a safer working place, generate less waste, and allow students to increase their knowledge in new environmentally friendly…

All-solid-state polymer electrolytes (SPEs) have been regarded as an advisible alternative for simultaneously overcoming the safety issues and high energy density demands presented in traditional lithium batteries, and they represent the development orientation of energy storage devices. This course describes the preparation of a cross-linked and…

We describe a 2 h general-chemistry experiment that introduces college students not only to the concepts, synthesis, and applications of nanomaterials at an early stage but also the use of a spectrophotometer for quantification and unknown determination based on Beer's Law. The procedure involves students (1) preparing a nanocomposite by…

A multistep synthesis of a metal-free organic dye-sensitizer for solar cells was developed as a multifaceted research project for upper-division undergraduate students with a goal of introducing students to the application of organic synthesis in material science, and renewable energy research. The characterization of the dye is done by thin-layer…

In this laboratory teaching experiment, commercial cannabis oils were analyzed by undergraduate organic chemistry students using gas chromatography-mass spectrometry (GC-MS) to investigate three isomeric cannabinoids commonly found in cannabis products: cannabidiol (CBD), [delta][superscript 9]-tetrahydrocannabinol ([delta][superscript 9]-THC),…

This manuscript introduces a novel General Chemistry experiment designed to incorporate modern instrumental methods and bioinspired materials in the context of marine environments and sustainability. The experiment explores the influence of collagen on the formation of calcium carbonate (CaCO[subscript 3]) polymorphs over two 2 h lab sessions,…

The free radical chlorination of an alkane experiment is often used in the undergraduate laboratory curriculum to introduce students to the free radical mechanism, substituent effects, intermediate stability, and the relative reactivity of radicals. In this experiment, students monochlorinate multiple alkanes and analyze the reaction mixture using…

Inductively coupled plasma optical emission spectroscopy (ICP-OES) is one of the most commonly used analytical techniques for the measurement of metals in environmental matrices. However, one of the drawbacks of ICP-OES is interference, viz., spectral and nonspectral (due to transport effects) interference. In this simple laboratory experiment,…

Keto-enol tautomerism is a special example of structural isomerism. In this experiment, 6-chlorofulvene is predominantly yielded during the chlorination reaction of 6'-hydroxyfulvene with POCl[subscript 3] in the presence of DMF. The high regioselectivity of this reaction is dominated by intramolecular hydrogen-bonding and steric hindrance,…

Plants encounter several different threats that affect their well-being during the spring. With chemistry, plants may defend themselves from, for example, excess UV-radiation and herbivores. The defense compounds between plant species vary, which makes it possible to utilize chemistry in identifying the plant species. In this laboratory…