Prior research has suggested that Project Based Learning (PBL) may affect students' performance. Nevertheless, there has been a lack of empirical studies that have examined these relationships specially, in Bachelor's Degrees and Master's degrees. This research empirically examines whether PBL improves Own apprenticeship abilities' development as well as promotes Students' subject overcoming and their professional success using data from 65 Spanish University students. Results of this study show that using PBL methodology in lessons enhances the students' Own apprenticeship abilities' development. These results demonstrate the power of over students' subject overcoming and their professional success. They display that students' subject overcoming may play a mediating role in the relationship between PBL and students' professional success. Moreover, these results cover an existing gap in literature, since there is no empirical literature that has tried to link as a whole PBL, Own apprenticeship abilities' development, Students' subject's overcoming and their Professional success.