Objective: College students, particularly first-year students, are at risk for alcohol misuse and alcohol-related consequences (e.g., condomless sex). Our objective was to determine if first- and second-year students were more or less likely to report any act of condomless sex under the influence of alcohol than third- and fourth-year students. Participants: Participants (N = 447) were undergraduate students recruited from a private institution in Massachusetts. Methods: Logistic regression models were used to analyze differences in reported acts of condomless sex under the influence of alcohol in the past 30 days, by class rank. Results: First- and second-year students had lower odds (OR 0.40, 95% CI: 0.252-0.648) of reporting condomless sex under the influence of alcohol than third- and fourth-year students. Conclusions: Implications from these results can contribute to understanding sexually transmitted infections in the college population.