To examine whether need for approval (NFA) and antisocial behavior (ASB) moderate the effects of socioemotional stimuli on cognitive control, 88 girls (M[subscript age] = 16.31 years; SD = 0.84; 65.9% White) completed a socioemotional Go/No-go and questionnaires. At high approach NFA, girls responded more slowly during appetitive than control (b = -8.80, p < 0.01) and aversive (b = -5.58, p = 0.01) trials. At high ASB, girls responded more slowly (b = -6.12, p = 0.02) and less accurately (OR = 1.11, p = 0.03) during appetitive than aversive trials; at low ASB, girls responded more slowly during aversive than control trials (b = -4.42, p = 0.04). Thus, both context and individual differences influence adolescents' cognitive control.