This book was written to help introductory biology teachers gain a basic understanding of contemporary bioinstrumentation and the uses to which it is put in the laboratory. It includes topics that are most basic to understanding the nature of biology. The book is divided into five sections: (1) "Separation and Identification" that includes chapters on electrophoresis, chromatographic techniques, immunologic methods, flow cytometry, and centrifugation of biomolecules; (2) "Observation" that includes chapters on advances in light microscopy, transmission electron microscopy, and scanning electron microscopy; (3) "Spectroscopy" that includes chapters on absorption spectroscopy, fluorescence spectroscopy, cross-sectional medical imaging, and infrared spectroscopy; (4) "Biological Tracing and Sensing" that includes a chapter on radionuclides; and (5) "Manipulation of Biological Molecules" that includes chapters on recombinant DNA, the polymerase chain reaction, and restriction fragment length polymorphisms. Chapter overviews, concept maps, margin notes, photos of real scientists and their students, overhead transparency masters, and an Internet bioinstrumentation web site directory are also included. (JRH)