Clustered regularly interspaced short palindromic repeats (CRISPR) are a revolutionary tool based on a bacterial acquired immune response system. CRISPR has gained widespread use for gene editing in a variety of organisms and is an increasingly valuable tool for basic genetic research, with far-reaching implications for medicine, agriculture, and…

The different reactivities between 1°, 2°, and 3° butyl chlorides by the unimolecular nucleophilic substitution (S[subscript N]1) mechanism were easily observed at 60 °C by a solvolysis reaction in ethanol with ether formation. The hydrogen ion from the byproduct HCl reacted with an acid--base indicator such as methyl red to induce a color change.…

An experiment for the upper-division undergraduate biochemistry laboratory is described in which students investigate the influence of genetic variations of cytochrome P450 1A2 on drug metabolism, using caffeine as a model compound. Saliva samples from human subjects are characterized for a single-nucleotide polymorphism in the CYP1A2 gene…

This article describes the use of a spreadsheet to reinforce basic calculus that is expected of all university-level chemistry majors. The example provided shows a calculation using Excel to estimate, using a Riemann summation, the radiant exitance of a hot object using Planck's Law of Blackbody Radiation. The approach reinforces the elementary…

Disrupting a gene to determine its effect on an organism's phenotype is an indispensable tool in molecular biology. Such techniques are critical for understanding how a gene product contributes to the development and cellular identity of organisms. The explosion of genomic sequencing technologies combined with recent advances in genome-editing…

Space science is perhaps the science topic that elicits the greatest interest in students in the United States and also worldwide. NASA has always endeavored to leverage that widespread interest to advance STEM education, not least because NASA requires a thriving STEM workforce for the future.

We present an accessible implementation of augmented reality projections for the depiction of complex structures and motifs, including atomic orbitals and elemental allotropes. The utilization of a free, cross-platform-compatible, online database of these structures provides the access route for closer examination, either via augmented reality or…

This modular, open-framework capstone course delves deeply into the synthesis, separation, and characterization of chiral molecules while teaching critical thinking and writing skills in a research-like setting within a fertile area for discovery. This course has evolved over 30 years and has been in its present form for 5 years at the time of…

This communication describes the actions undertaken to translate the chemical crystallography course at the University of Novi Sad, Serbia, from face-to-face to online instruction, as well as the emerging challenges encountered during this unprecedented time. As part of the global efforts to respond to the recent disruptions to teaching, our…

We present our experience with transferring a four-day photometry and dye-adsorption laboratory experiment to the kitchens of students of Applied Thermodynamics from our degree in "Industrial Chemical Process Engineering". The students designed and built a double-beam photometer using their smartphones and household materials, then…

An organic solar cell fabrication kit has been developed for demonstration in both undergraduate teaching classes and high school laboratories to promote the growing field of renewable energy and to facilitate empirical comprehension of solar technology. The laboratory focuses on fabricating organic photovoltaics (solar cells) and testing the…

Using everyday life examples is proven didactically useful for teaching physics, as it presents effective applications of physical laws. Cooking and food, in particular, serve two useful purposes: on one side, they are able to engage students in the study of physics with familiar examples; on the other side, thanks to the wide range of physical…

Enhancing student employability is a key aspect of any chemistry-based degree; however, embedding such activities in the curriculum is often challenging. Placements (internships in the USA) or experiential visits are the most widely used approach, but these are not always inclusive. Work-integrated learning (WIL), the practice of combining…

In this study, we analyzed the literature on teaching or learning on a topic in Earth science, environmental science, or climate change between 1995 and 2017. We investigated the length of the intervention, intervention setting and instructional level, instructional purpose, pedagogical framing and pedagogical methods (including what materials and…

Following sustained discussion regarding the relationship between advanced mathematics and science learning in England, the government has pursued a reform agenda in which mathematics is embedded in national, high stakes A-level science qualifications and their assessments for 18-year-olds. For example, A-level Chemistry must incorporate the…