The chemistry of 4d and 4f metals was investigated at the undergraduate level in an effort to incorporate f-element chemistry in the curriculum. This was accomplished through microwave-assisted synthesis of 1,10-phenanthroline (phen) coordination compounds [Eu(phen)(subscript 3)](PF[subscript 6])[subscript 3] and [Ru(phen)(subscript…

Electrochemistry is taught in most undergraduate chemistry programs. Although this topic is important for students due to its broad interest in industry (energy, diagnostics, car industry, etc.), they often find it difficult, because it is based on a combination of various physical concepts such as electric fields, interfacial processes or charge…

Chemistry and biochemistry instructors must help students to develop the ability to visualize and manipulate 3D biomolecular structures and critically analyze them and their relationship to their functions. To do this, representative systems must be strategically selected to stimulate students' motivation. Since the World Health Organization…

Evolutionary medicine is a growing area of research and practice; however, it is not widely discussed in introductory biology courses. Because of the interest in human biology, using evolutionary medicine is a great way to hold students' interest, placing topics in context, making the subject of evolution relevant. Too often students lose interest…

An efficient synthesis of the exorbitantly priced Lambert-Eaton myasthenic syndrome drug amifampridine was developed and applied in the second-semester undergraduate organic chemistry laboratory. The two-step synthesis entails a nucleophilic aromatic substitution reaction of commercial 4-chloro-3-nitropyridine with methanolic ammonia to afford…

Offering an advanced organic chemistry course at a primarily undergraduate institution poses a challenge of condensing graduate organic synthesis into one course. This course was designed so students choose and read recent total synthesis papers from the literature in lieu of relying on a textbook or other pre-existing course materials. Following…

Apurinic/apyrimidinic (AP or abasic) sites are deoxyribonucleic acid (DNA) lesions that result from the loss of a nucleobase by hydrolysis of the "N"-glycosyl bond. AP sites are the most frequent lesions in cells and are caused by environmental and cancer therapeutic genotoxins. Herein, the bicinchoninic colorimetric assay, typically…

Laboratory astrophysics and astrochemistry are emerging fields highlighting the importance of laboratory simulations and experiments to benefit remote observations. In particular, ice mixtures found in the outer solar system may offer insight into the early evolution of organic molecules. H[subscript 2]O-ice mixtures containing other species such…

The trajectory of a ball rolling across an inclined plane was recorded on video film to determine if it followed a parabolic path as others have suggested. The challenges in this case were (a) to determine the magnitude and direction of the friction force on the ball, (b) to determine the effect of the friction force on the trajectory and (c) to…

As a model study for improving undergraduate organic chemistry laboratories with contemporary research concepts and practices, we evaluated a project module aiming at the synthesis of two porphyrin compounds. The module was implemented in a format that differed in several ways from that of a traditional course. It was designed for small student…

This paper presents two low-cost hands-on activities designed to enhance student understanding and address the pedagogical challenges faced by microbiology professors in teaching concepts related to cell structure and gene regulation. In the first activity, we used Shrinky Dinks and Jeopardy-style game questions to explore the differences between…

Academic integrity is often a concern instructors have when teaching, with past research indicating the classroom environment is one of the largest factors in determining students' likelihood to cheat. In this commentary, we intend to start a dialogue with instructors regarding the importance of creating a classroom environment that values…

Antioxidants are molecules that act against free radicals, and this effect can bring many benefits to health and society. Antioxidants can be found in various matrices of nature, such as fruits and plants. Some studies have shown that "Rhizophora mangle," a typical mangrove plant, is rich in antioxidants. People report its use for…

Enzymes, enzymatic kinetics, and enzyme inhibition are topics covered in undergraduate biochemistry textbooks, having perceptible relevance to everyday life. The experimental use of enzymes involved in basic physiologic processes may be of utmost pedagogic interest because they bring evidence on how a significant number of drugs are used to…

This work further implements the "elements of inquiry" approach in a first-year undergraduate laboratory course, in a two-part inquiry sequence. In the first part of the sequence, students iteratively develop a "best-practice" TLC procedure. In the second part, students iteratively optimize a simple organic reaction using TLC,…