The central dogma of molecular biology describes the transfer of genetic information from nucleic acids to proteins and stipulates that the system cannot work in the reverse direction. As a fundamental principle in biology, the dogma is as influential as it is controversial. Some commentators have debated the central dogma's empirical accuracy…

Transcription is the critical first step in expressing a gene, during which an RNA polymerase (RNAP) synthesizes an RNA copy of one strand of the DNA that encodes a gene. Here we describe a laboratory experiment that uses a single assay to probe two important steps in transcription: (1) RNAP binding to DNA, and (2) the transcriptional activity of…

The central argument of this article is that abduction as a "mode of inference" is a key element in the nature of scientists' science and should consequently be introduced in school science. Abduction generally understood as generation and selection of hypotheses permits to articulate the classical scientific contexts of discovery and…

In 1900, three botanists claimed they had found regularities in inheritance, which soon would be known as Mendel's Laws, without knowing the work of Gregor Mendel or of each other. Their claims of independent (re)discovery have been thoroughly studied during the past decades, with various outcomes. The case is still of interest today as it offers…

The worldwide impact of the COVID-19 pandemic has been enormous. It has affected the justification of the contributions from academia, and resulted in rapid spreading of misinformation and conspiracy theories. The use of the social media has during the pandemic intermixed the space between the private and the public domain, and has interfered with…

Countercurrent multiplication (CCM) is widely accepted as the mechanism for the generation of the corticopapillary osmotic gradient in the outer medulla of mammalian kidneys. However, several issues in the literature cause the current explanations of CCM to be inefficient and incomplete. As a result, it is challenging to clearly explain CCM in…

Have you ever deeply considered the intersections between research and education, particularly for second-level students? Traditionally, the convergence of these two realms is most often noted when considering the integration of research findings into educational practices or the involvement of, typically a small number, of students in research…

In anatomical research and education, three-dimensional visualization of anatomical structures is crucial for understanding spatial relationships in diagnostics, surgical planning, and teaching. While computed tomography (CT) and magnetic resonance imaging (MRI) offer valuable insights, they are often expensive and require specialized resources.…

The COVID-19 pandemic provides an opportunity for teachers to explicitly address nature of science (NOS) themes during instruction. Aligned with key NOS categories in the "Next Generation Science Standards," this article discusses events and trends from the pandemic that teachers can use to help students understand values and methods of…

Michael Faraday is considered one of the greatest science lecturers in history. He popularized the Christmas Lectures as a format of science communication that has survived until today in the Royal Institution of Great Britain. Especially, his "Chemical History of a Candle" has become a classic of science communication that has inspired…

Research reproducibility is essential for scientific development. Yet, rates of reproducibility are low. As increasingly more research relies on computers and software, efforts for improving reproducibility rates have focused on making research products digitally available, such as publishing analysis workflows as computer code, and raw and…

Nested hierarchical structure is one of life's most familiar properties and a major component of biological diversity and complexity. However, there is little effort to teach the evolution of the hierarchy of life, as there is little effort to teach biological complexity per se. We propose a framework for teaching biological complexity based on…

Aragón, Acevedo-Díaz and García-Carmona study prospective biology teachers' understanding of the Nature of Science (NOS). In my comment, I would first like to step back and ask "what it is to understand something", i.e. the sciences. I will turn to a quasi-Wittgensteinian epistemological tradition and suggest that, contrary to our habit…

Despite advances in discussions about the nature of science, there is still a paucity of discussion on the ontological dimension of science in science education research that makes it difficult to defend its content and teaching. In this article, the reasons for trusting science and science education are analyzed through three arguments. The first…

As a cross-cutting and comprehensive subject, medicinal chemistry involves the knowledge of chemical, biological, medical, and pharmaceutical sciences. A comprehensive medicinal chemistry experience for undergraduates is expected to train various experimental skills and enhance their scientific research ability. Herein, a series of laboratory and…