A prescriptive statement is a recommendation that, if a course of action is taken, then a desirable outcome will likely occur. For example, in reading research recommending that teachers apply an intervention targeted at a specific reading skill to improve children's reading performance is a prescriptive statement. In our view, these statements…

Discusses major uses of rats as experimental animals for studying health concerns, pointing out that their size, gestation, and histocompatibility make them useful in various studies. Topic areas addressed include aging, autoimmune disease, genetics, cancer, diabetes, hypertension, infection, reproduction, and behavior. (DH)

The advantages and justifications for using small animals in human-oriented research are reviewed. Some of the pitfalls of extrapolating animal-derived data to humans are discussed. Several specific problems with animal experimentation are highlighted. (CW)

Perspectives, policy issues, and options for Congressional action that relate most directly to the development and implementation of alternatives to animal use in research and testing are addressed in this report. Testimonies and reports include those from the Office of Technology Assessment, the National Institute of Health, and the Food and Drug…

This report was written in response to quesions from the Subcommittee on Health and the Environment concerning the implementation by the National Institutes of Health (NIH) of National Research Service Awards (NRSAs) in each of the fiscal years 1986, 1987, and 1988 made available for research in primary medical care. Discussions in this report…

Investigates use of positron emission tomography (PET) to study in-vivo metabolic processes. Discusses methodology of PET and medical uses. Outlines the production of different radioisotopes used in PET radiotracers. Includes selected bibliography. (ML)

Proposes the triangulation of two qualitative research methods, hermeneutics and grounded theory, to illuminate clinical realities that elude alternative approaches. Discusses how hermeneutics reveals perceptual information about the uniqueness of shared meanings and common practices, and how grounded theory provides a conceptual framework useful…

In response to the President's Office of Science and Technology Policy request to identify promising areas for U.S. research investment in science and technology, this report contains briefings by outstanding researchers in several fields of science. This volume is the fifth in a series of briefings which are used to anticipate important new…