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Peer reviewed
Direct linkMo´nica I. Garci´a-Aranda; Marco Franco-Pe´rez; Angel Zamudio-Medina – Journal of Chemical Education, 2023
Heterocyclic compounds are an integral part of research, particularly in the pharmaceutical field. The synthesis of such compounds in an undergraduate laboratory can help students understand the relevance and importance of their field of study. Our experimental activity introduces a novel procedure to synthesize coumarin, a heterocyclic formed by…
Descriptors: Undergraduate Students, College Science, Chemistry, Laboratory Experiments
Larouche, Olivier; Jolicoeur, Ludovic; Calosi, Piero – Journal of Biological Education, 2020
Changes in environmental conditions can have a profound impact on organismal processes. For aquatic organisms, changes in dissolved oxygen concentration can have major repercussions, notably for physiological processes that have high long-term energetic costs and are more likely to rely on aerobic metabolic pathways. Here we propose a simple…
Descriptors: College Science, Science Activities, Marine Biology, Science Instruction
Siddiqui, Khawar S.; Poljak, Anne; Ertan, Haluk; Bridge, Wallace – Biochemistry and Molecular Biology Education, 2022
Determination of enzyme activity is crucial for discovery, research, and development in life sciences. The activity of enzymes is routinely determined using spectrophotometric assays that measure rates of substrate consumption or product formation. Though colorimetric-based detection systems are simple, rapid, and economical to perform, the…
Descriptors: Biochemistry, Biological Sciences, College Science, Heat
Faville, Scott C.; Harris-Hamdscomb, Kes; Harker, Owain; Mattison, Stephanie; Tamorite, Hajie; Bristowe, Joshua; Daly, Daniel; Ege, Raissa; He, Haoyuan; Jones, Julian; McCorkindale, Abby; Mei, Kerry; Monson, Ashleigh; Moree, Lana; Perkovic, Finley; Rickerby, Georgia; Robinson, Jack; Rudkin, Felix; Whibley, Luke; Worthington, Rebecca; Ennis, Courtney; de la Harpe, Sara; Brind, Thomasin; Hopkins, Andrew; Winefield, Kaleb; Hendrickx, Sarah; Caljon, Guy; Perry, Benjamin; Vernall, Andrea J. – Journal of Chemical Education, 2022
An undergraduate laboratory was developed as part of the Drugs for Neglected Diseases "initiative's" Open Synthesis Network. This activity aimed to develop new compounds efficacious against visceral leishmaniasis. Students successfully synthesized, purified, and characterized ten different benzoxazole amides that were sent for biological…
Descriptors: College Science, Undergraduate Students, Laboratory Experiments, Diseases
Keira D. Naff; Jeri L. Tyler; Dima H. Hamza; Jonathan D. White – Journal of Chemical Education, 2023
Structure--activity relationships are foundational concepts in biochemistry and drug design. Despite their importance, it can be difficult to create and execute laboratory activities that allow students to directly observe the interactions between small-molecule drugs and their biomolecular targets. Here, we report an activity that investigates…
Descriptors: Genetics, Undergraduate Students, Undergraduate Study, College Science
Dounay, Amy B.; O'Donnell, Martin J.; Samaritoni, J. Geno; Popiolek, Lukasz; Schirch, Douglas; Biernasiuk, Anna; Malm, Anna; Lamb, Isaac W.; Mudrack, Kristen; Rivera, Daniel G.; Ojeda, Gerardo M.; Scott, William L. – Journal of Chemical Education, 2019
An experiment for the synthesis of N-acyl derivatives of natural amino acids has been developed as part of the Distributed Drug Discovery (D3) program. Students use solid-phase synthesis techniques to complete a three-step, combinatorial synthesis of six products, which are analyzed using LC-MS and NMR spectroscopy. This protocol is suitable for…
Descriptors: Organic Chemistry, Laboratory Experiments, Science Experiments, Pharmacology
Cybulskis, Viktor J.; Gawecki, Piotr; Zvinevich, Yury; Gounder, Rajamani; Ribeiro, Fabio H. – Journal of Chemical Education, 2021
A versatile and portable apparatus was developed to demonstrate exciting visual displays of catalytic phenomena that introduce basic concepts in catalysis, renewable energy, and chemical safety, in order to pique scientific curiosity in a variety of audiences including middle and high school students, undergraduate and graduate students, and the…
Descriptors: Science Instruction, Chemistry, Scientific Concepts, Concept Formation
Waleed Alahmad; Somsak Pianwanit; Luxsana Dubas; Charoenkwan Kraiya – Journal of Chemical Education, 2023
The COVID-19 pandemic has significantly affected teaching processes worldwide, particularly in laboratory-intensive courses. To adapt, online experiments have been implemented globally. In response, educators at the Department of Chemistry, Chulalongkorn University, developed a Lab@Home chemistry experiment for their general chemistry lab course…
Descriptors: Chemistry, Science Laboratories, Laboratory Experiments, Scientific Concepts
Geisert, Rodney D.; Smith, Michael F.; Schmelzle, Amanda L.; Green, Jonathan A. – Advances in Physiology Education, 2018
In this teaching laboratory, the students are directed in an exercise that involves designing and performing an experiment to determine estrogen's role in regulating delayed implantation (diapause) in female rats. To encourage active participation by the students, a discussion question is provided before the laboratory exercise in which each…
Descriptors: Birth, Biology, Animals, Science Instruction
Baldwin, Nicole; Orgill, MaryKay – Chemistry Education Research and Practice, 2019
Practicing chemists use models, diagrams, symbols, and figures to represent phenomena which cannot be detected by the human senses. Although research suggests that these external representations (ERs) can also be used to address the challenges that students have in learning chemistry, it is not clear how instructors' use of ERs aligns with their…
Descriptors: Teaching Assistants, College Science, Chemistry, Science Laboratories
Bracker, Rachel; Dominguez, Kimberly; Stender, Anthony S. – Journal of Chemical Education, 2020
Nanoparticles are an increasingly important tool in chemistry research, but currently there are few opportunities for chemistry students to work with nanoparticles in undergraduate analytical courses. In this exercise, designed for an analytical or instrumental analysis lab course, students have the opportunity to work with solutions of silver…
Descriptors: Chemistry, Undergraduate Students, Science Activities, Science Instruction
Download full textGerard G. Dumancas; Noemi Carreto; Oliver Generalao; Guoyi Ke; Ghalib Bello; Arnold Lubguban; Roberto Malaluan – Journal of Chemical Education, 2023
Chemometric techniques such as partial least-squares (PLS) regression have been applied with huge success to a wide array of chemical problems including multicomponent analysis of analytes in complex mixtures. Despite this, there are few examples of laboratory pedagogical exercises that involve students in the acquisition of chemical data from…
Descriptors: Undergraduate Students, College Science, Chemistry, Science Laboratories
Tyler A. Shaffer; Carlos U. Herrada; Avery M. Walker; Laura D. Casto-Boggess; Lisa A. Holland; Timothy R. Johnson; Megan E. Jones; Yousef S. Elshamy – Journal of Chemical Education, 2023
Electrophoresis is integral to analytical and biochemistry experiences in undergraduate education; however, fundamental principles of the method are often taught in upper-level laboratories through hands-on experiences. A laboratory activity is reported that teaches the concepts of electrophoretic mobility and electroosmotic flow. A single…
Descriptors: Chemistry, Science Instruction, Teaching Methods, Cost Effectiveness
Wan, Tong; Geraets, Ashley A.; Doty, Constance M.; Saitta, Erin K. H.; Chini, Jacquelyn J. – International Journal of STEM Education, 2020
Graduate teaching assistants (GTAs) often lead laboratory and tutorial sections in science, technology, engineering, and mathematics (STEM), especially at large, research-intensive universities. GTAs' performance as instructors can impact student learning experience as well as learning outcomes. In this study, we observed 11 chemistry GTAs and 11…
Descriptors: Teaching Assistants, Graduate Students, Teaching Methods, College Science
Robinson, Rebekah L.; Neely, Amy E.; Mojadedi, Wais; Threatt, Katie N.; Davis, Nicole Y.; Weiland, Mitch H. – Biochemistry and Molecular Biology Education, 2017
The concepts of protein purification are often taught in undergraduate biology and biochemistry lectures and reinforced during laboratory exercises; however, very few reported activities allow students to directly gain experience using modern protein purification instruments, such as Fast Protein Liquid Chromatography (FPLC). This laboratory…
Descriptors: College Science, Active Learning, Chemistry, Science Laboratories
