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Direct linkWei Zhu; Fei Yan; Jianfeng Zhu; Linzi Zhu; Fengyu Liu – Research Ethics, 2024
This paper describes a scoping review of China's academic resource databases, relevant official websites, news reports and public accounts spanning a period from the end of 2019 to the end of 2022, to investigate the challenges in scientific integrity and ethical soundness of research conducted during and immediately after the COVID-19 pandemic in…
Descriptors: Foreign Countries, Ethics, Integrity, Research Methodology
Emma Law; Isabel Smith – Research Ethics, 2024
During the COVID-19 pandemic, the race to find an effective vaccine or treatment saw an 'extraordinary number' of clinical trials being conducted. While there were some key success stories, not all trials produced results that informed patient care. There was a significant amount of waste in clinical research during the pandemic which is said to…
Descriptors: Ethics, Research Methodology, Integrity, COVID-19
Tambornino, Lisa; Lanzerath, Dirk – Research Ethics, 2020
To reduce the global burden of the COVID-19 pandemic, there is an urgent need to develop a safe vaccine. Vaccine development usually takes many years as it goes through several different phases. To hasten COVID-19 vaccine development, it has been suggested that the final stage could be replaced with a human challenge trial (HCT). Volunteers would…
Descriptors: COVID-19, Pandemics, Immunization Programs, Ethics
Bompart, Francois – Research Ethics, 2020
Hundreds of clinical trials of potential treatments and vaccines for the "coronavirus 19 disease" (COVID-19) have been set up in record time. This is a remarkable reaction to the global pandemic, but the absence of a global coordination of clinical research efforts raises serious ethical concerns. Some COVID-19 patients might carry the…
Descriptors: COVID-19, Pandemics, Medical Research, Ethics
Chappell, Richard Yetter; Singer, Peter – Research Ethics, 2020
There is too much that we do not know about COVID-19. The longer we take to find it out, the more lives will be lost. In this paper, we will defend a principle of "risk parity": if it is permissible to expose some members of society (e.g. health workers or the economically vulnerable) to a certain level of "ex ante" risk in…
Descriptors: COVID-19, Pandemics, Medical Research, Risk
Kumar, Nandini K.; Muthuswamy, Vasantha – Research Ethics, 2020
The COVID-19 pandemic has brought unprecedented, major challenges to the ethical conduct of research including challenges for the rapid and robust ethical review of biomedical research. The Indian Council of Medical Research's "National Guidelines for Ethics Committees Reviewing Biomedical and Health Research during COVID-19 Pandemic"…
Descriptors: COVID-19, Pandemics, Medical Research, Ethics
