Mediation analysis in Single Case Experimental Designs (SCEDs) evaluates intervention mechanisms for individuals. Despite recent methodological developments, no clear guidelines exist for maximizing power to detect the indirect effect in SCEDs. This study compares frequentist and Bayesian methods, determining (1) minimum required sample size to…

We have entered an era in which scientific evidence increasingly informs research practice and policy. As there is an exponential increase in the use of single-case experimental designs (SCEDs) to evaluate intervention effectiveness, there is accumulating evidence available for quantitative synthesis. Consequently, there is a growing interest in…

In 2020, the What Works Clearinghouse (WWC) for single-case experimental design (SCED) studies released an updated version of their standards and procedures handbook (Version 4.1). Because of these updates, there is a need to understand the implications for the field in terms of quality rating of the design, and subsequent synthesis of evidence at…