From an understanding of knowledge mobilisation as a set of strategies that favour responsible and inclusive research, the aim of this paper is to identify the obstacles or barriers to carrying out such research in higher education institutions, as perceived by researchers. In this descriptive study, content analysis is used to examine semi-structured interviews carried out with eighty research groups from five European countries (Austria, Romania, Serbia, Slovenia and Spain) that participated in the research. Results reveal the main barriers researchers perceived are associated with social commitment, relational aspects, encouragement to participate (attitudinal, organisational and institutional barriers) and knowledge mobilisation practices (derived from the research process and research evaluation policies). Ethical and policy implications for more responsible and inclusive research are drawn in the conclusions.