Adolescents who struggle in the area of literacy tend to experience difficulty accessing texts across many different content areas. These students could benefit from increased collaborative interactions between general education content area teachers, special education teachers, and other school personnel with expertise in the area of literacy such as reading specialists. This article discusses the use of a literacy strategy, Question Answer Relationships (QAR), which is designed to help students having difficulty in the area of reading comprehension. The QAR strategy can be generalized to help students across a variety of content areas. Details are provided about how teachers can engage in collaborative planning and instruction in an effort to promote generalization of the QAR strategy across content areas. (Contains 3 tables and 1 figure.)