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Gornick, M. C.; Addington, A. M.; Sporn, A.; Gogtay, N.; Greenstein, D.; Lenane, M.; Gochman, P.; Ordonez, A.; Balkissoon, R.; Vakkalanka, R.; Weinberger, D. R.; Rapoport, J. L.; Straub, R. E. – Journal of Autism and Developmental Disorders, 2005
Straub "et al." ("2002") recently identified the 6p22.3 gene dysbindin (DTNBP1) through positional cloning as a schizophrenia susceptibility gene. We studied a rare cohort of 102 children with onset of psychosis before age 13. Standardized ratings of early development, medication response, neuropsychological and cognitive performance, premorbid…
Descriptors: Psychosis, Children, Cohort Analysis, Clinical Diagnosis

Mechanic, David – Social Forces, 1972
Descriptors: Behavior Patterns, Environmental Influences, Family Life, Genetics
National Inst. of Mental Health (DHEW), Rockville, MD. – 1977
The 14 conference papers on mental illness focus on the biological, genetic, psychopharmacological, psychopathological, and epidemiological and social factors related to psychoses. Divided into five sections each preceded by a brief introduction, entries include the following titles and authors: "The Biological Substrates of Schizophrenia" (S.…
Descriptors: Biological Influences, Conference Reports, Drug Therapy, Emotional Disturbances
fMRI Correlates of State and Trait Effects in Subjects at Genetically Enhanced Risk of Schizophrenia
Whalley, Heather C.; Simonotto, E.; Flett, S.; Marshal, I.; Ebmeier, K. P.; Owens, D. G. C.; Goddard, N. H.; Johnstone, E. C.; Lawrie, S. M. – Brain, 2004
Schizophrenia is a highly heritable disorder that typically develops in early adult life. Structural imaging studies have indicated that patients with the illness, and to some extent their unaffected relatives, have subtle deficits in several brain regions, including prefrontal and temporal lobes. It is, however, not known how this inherited…
Descriptors: Schizophrenia, Genetics, Correlation, Heredity
Schopler, Eric; Loftin, Julie – J Abnorm Psychol, 1969
Research supported in part by General Research Support Award No. FR-05406 from the United States Public Health Service.
Descriptors: Adults, Cognitive Processes, Concept Formation, Genetics